Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms

MJ Peluso, AN Deitchman, L Torres, NS Iyer… - Cell Reports, 2021 - cell.com
We describe severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific T cell
responses, soluble markers of inflammation, and antibody levels and neutralization capacity …

Dynamics of CD4 T cell and antibody responses in COVID-19 patients with different disease severity

M Koblischke, MT Traugott, I Medits, FS Spitzer… - Frontiers in …, 2020 - frontiersin.org
Disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
ranges from mild illness to severe respiratory disease and death. In this study, we …

Reactive T cells in convalescent COVID-19 patients with negative SARS-CoV-2 antibody serology

S Steiner, T Schwarz, VM Corman, F Sotzny… - Frontiers in …, 2021 - frontiersin.org
Despite RT-PCR confirmed COVID-19, specific antibodies to SARS-CoV-2 spike are
undetectable in serum in approximately 10% of convalescent patients after mild disease …

[HTML][HTML] Duration of post–COVID-19 symptoms is associated with sustained SARS-CoV-2–specific immune responses

JK Files, S Sarkar, TR Fram, S Boppana, S Sterrett… - JCI insight, 2021 - ncbi.nlm.nih.gov
A subset of COVID-19 patients exhibit post-acute sequelae of COVID-19 (PASC), but little is
known about the immune signatures associated with these syndromes. We investigated …

Phenotype and kinetics of SARS-CoV-2–specific T cells in COVID-19 patients with acute respiratory distress syndrome

D Weiskopf, KS Schmitz, MP Raadsen, A Grifoni… - Science …, 2020 - science.org
SARS-CoV-2 has been identified as the causative agent of a global outbreak of respiratory
tract disease (COVID-19). In some patients, the infection results in moderate to severe acute …

SARS-CoV-2-specific T cells associate with inflammation and reduced lung function in pulmonary post-acute sequalae of SARS-CoV-2

KM Littlefield, RO Watson, JM Schneider… - PLoS …, 2022 - journals.plos.org
As of January 2022, at least 60 million individuals are estimated to develop post-acute
sequelae of SARS-CoV-2 (PASC) after infection with severe acute respiratory syndrome …

Durability of SARS-CoV-2–specific T-cell responses at 12 months postinfection

Z Lu, ED Laing, J Pena DaMata… - The Journal of …, 2021 - academic.oup.com
Background Characterizing the longevity and quality of cellular immune responses to severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enhances understanding of …

Divergent SARS‐CoV‐2‐specific T‐and B‐cell responses in severe but not mild COVID‐19 patients

AE Oja, A Saris, CA Ghandour… - European journal of …, 2020 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is the causative agent of
the current coronavirus disease 2019 (COVID‐19) pandemic. Understanding the immune …

[HTML][HTML] COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses

A Bonifacius, S Tischer-Zimmermann, AC Dragon… - Immunity, 2021 - cell.com
Cellular and humoral immunity to SARS-CoV-2 is critical to control primary infection and
correlates with severity of disease. The role of SARS-CoV-2-specific T cell immunity, its …

Decline in neutralising antibody responses, but sustained T‐cell immunity, in COVID‐19 patients at 7 months post‐infection

J Chen, X Liu, X Zhang, Y Lin, D Liu… - Clinical & …, 2021 - Wiley Online Library
Objectives This study aimed to explore the severe acute respiratory syndrome coronavirus 2
(SARS‐CoV‐2)‐specific humoral responses and T‐cell responses in patients who have …