Translating concepts of neural repair after stroke: Structural and functional targets for recovery

RW Regenhardt, H Takase, EH Lo… - Restorative neurology …, 2020 - content.iospress.com
Stroke is among the most common causes of adult disability worldwide, and its disease
burden is shifting towards that of a long-term condition. Therefore, the development of …

Targets for neural repair therapies after stroke

ST Carmichael - Stroke, 2010 - Am Heart Assoc
Studies of neural repair after stroke have developed from a relatively small number of
laboratories doing highly creative discovery science to a field in which reproducible …

Emergent properties of neural repair: elemental biology to therapeutic concepts

ST Carmichael - Annals of neurology, 2016 - Wiley Online Library
Stroke is the leading cause of adult disability. The past decade has seen advances in basic
science research of neural repair in stroke. The brain forms new connections after stroke …

Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic

ZG Zhang, M Chopp - The lancet neurology, 2009 - thelancet.com
Restorative cell-based and pharmacological therapies for experimental stroke substantially
improve functional outcome. These therapies target several types of parenchymal cells …

Translating the frontiers of brain repair to treatments: starting not to break the rules

ST Carmichael - Neurobiology of disease, 2010 - Elsevier
The field of neural repair in stroke has identified cellular systems of reorganization and
possible molecular mechanisms. Conceptual barriers now limit the generation of clinically …

Neurorestoration after stroke

TD Azad, A Veeravagu, GK Steinberg - Neurosurgical focus, 2016 - thejns.org
Recent advancements in stem cell biology and neuromodulation have ushered in a battery
of new neurorestorative therapies for ischemic stroke. While the understanding of stroke …

Neuronal restoration following ischemic stroke: influences, barriers, and therapeutic potential

MP Kahle, GJ Bix - Neurorehabilitation and neural repair, 2013 - journals.sagepub.com
Neurogenesis, the birth of new neurons, occurs throughout life in the subventricular zone
and produces immature neurons that migrate tangentially through the rostral migratory …

Spontaneous and therapeutic-induced mechanisms of functional recovery after stroke

JM Cassidy, SC Cramer - Translational stroke research, 2017 - Springer
With increasing rates of survival throughout the past several years, stroke remains one of the
leading causes of adult disability. Following the onset of stroke, spontaneous mechanisms of …

[HTML][HTML] Enhancing endogenous capacity to repair a stroke-damaged brain: An evolving field for stroke research

LR Zhao, A Willing - Progress in neurobiology, 2018 - Elsevier
Stroke represents a severe medical condition that causes stroke survivors to suffer from long-
term and even lifelong disability. Over the past several decades, a vast majority of stroke …

Novel stroke therapeutics: unraveling stroke pathophysiology and its impact on clinical treatments

PM George, GK Steinberg - Neuron, 2015 - cell.com
Stroke remains a leading cause of death and disability in the world. Over the past few
decades our understanding of the pathophysiology of stroke has increased, but greater …