Efficacy of antifibrotic drugs, nintedanib and pirfenidone, in treatment of progressive pulmonary fibrosis in both idiopathic pulmonary fibrosis (IPF) and non-IPF: a …

JP Finnerty, A Ponnuswamy, P Dutta… - BMC Pulmonary …, 2021 - Springer
Abstract Background Research questions To compare the efficacy of nintedanib and
pirfenidone in the treatment of progressive pulmonary fibrosis; and to compare the efficacy of …

Comparing new treatments for idiopathic pulmonary fibrosis–a network meta-analysis

E Loveman, VR Copley, DA Scott, JL Colquitt… - BMC pulmonary …, 2015 - Springer
Background The treatment landscape for idiopathic pulmonary fibrosis, a devastating lung
disease, is changing. To investigate the effectiveness of treatments for idiopathic pulmonary …

Antifibrotic therapy for fibrotic lung disease beyond idiopathic pulmonary fibrosis

BF Collins, G Raghu - European Respiratory Review, 2019 - Eur Respiratory Soc
Two antifibrotic medications (nintedanib and pirfenidone) were recommended
(conditionally) for the treatment of patients with idiopathic pulmonary fibrosis (IPF) in the …

[HTML][HTML] Real-life comparison of pirfenidone and nintedanib in patients with idiopathic pulmonary fibrosis: A 24-month assessment

S Cerri, M Monari, A Guerrieri, P Donatelli, I Bassi… - Respiratory …, 2019 - Elsevier
Background Real-life data on the use of pirfenidone and nintedanib to treat patients with
idiopathic pulmonary fibrosis (IPF) are still scarce. Methods We compared the efficacy of …

Pirfenidone, nintedanib and N-acetylcysteine for the treatment of idiopathic pulmonary fibrosis: a systematic review and meta-analysis

P Rogliani, L Calzetta, F Cavalli, MG Matera… - Pulmonary …, 2016 - Elsevier
Background The prevalence of idiopathic pulmonary fibrosis (IPF) is increasing every year.
Pirfenidone and nintedanib were approved for treatment of IPF in 2014, but they received …

Systematic review and network meta-analysis of idiopathic pulmonary fibrosis treatments

K Fleetwood, R McCool, J Glanville… - Journal of managed …, 2017 - jmcp.org
BACKGROUND: The antifibrotics pirfenidone and nintedanib are both approved for the
treatment of idiopathic pulmonary fibrosis (IPF) by regulatory agencies and are …

Drug treatment of idiopathic pulmonary fibrosis: systematic review and network meta-analysis

WJ Canestaro, SH Forrester, G Raghu, L Ho… - Chest, 2016 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is a form of chronic progressive fibrosing
interstitial lung disease of unknown origin. Recently, nintedanib and pirfenidone …

Antifibrotic therapy for idiopathic pulmonary fibrosis: time to treat

TM Maher, ME Strek - Respiratory research, 2019 - Springer
Idiopathic pulmonary fibrosis (IPF) is a progressive disease with a dismal prognosis. The
average life expectancy of untreated patients with IPF is only 3 to 4 years. Decline in forced …

Impact of antifibrotic therapy on mortality and acute exacerbation in idiopathic pulmonary fibrosis: a systematic review and meta-analysis

T Petnak, P Lertjitbanjong, C Thongprayoon, T Moua - Chest, 2021 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung
disease associated with significant morbidity and mortality. Nintedanib and pirfenidone are …

Safety of nintedanib added to pirfenidone treatment for idiopathic pulmonary fibrosis

KR Flaherty, CD Fell, JT Huggins… - European …, 2018 - Eur Respiratory Soc
We assessed safety and tolerability of treatment with pirfenidone (1602–2403 mg· day− 1)
and nintedanib (200–300 mg· day− 1) in patients with idiopathic pulmonary fibrosis (IPF) …