[HTML][HTML] NLRP3 inflammasome activation and SARS-CoV-2-mediated hyperinflammation, cytokine storm and neurological syndromes
Despite the introduction of vaccines and drugs for SARS-CoV-2, the COVID-19 pandemic
continues to spread throughout the world. In severe COVID-19 patients, elevated levels of …
continues to spread throughout the world. In severe COVID-19 patients, elevated levels of …
[HTML][HTML] NLRP3 inflammasome activation in COVID-19: an interlink between risk factors and disease severity
NLRP3 inflammasome is a critical immune component that plays a crucial role in mounting
innate immune responses. The deleterious effects of inflammasome activation have been …
innate immune responses. The deleterious effects of inflammasome activation have been …
The NLRP3 inflammasome and COVID-19: Activation, pathogenesis and therapeutic strategies
N Zhao, B Di, L Xu - Cytokine & growth factor reviews, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), exhibits a wide spectrum of clinical presentations …
syndrome coronavirus 2 (SARS-CoV-2), exhibits a wide spectrum of clinical presentations …
[HTML][HTML] Common NLRP3 inflammasome inhibitors and Covid-19: divide and conquer
Severe SARS-CoV-2 infection causes systemic inflammation, cytokine storm, and
hypercytokinemia due to activation of the release of pro-inflammatory cytokines that have …
hypercytokinemia due to activation of the release of pro-inflammatory cytokines that have …
Targeting the NLRP3 inflammasome in severe COVID-19
TL Freeman, TH Swartz - Frontiers in immunology, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a member of the genus
Betacoronavirus within the family Coronaviridae. It is an enveloped single-stranded positive …
Betacoronavirus within the family Coronaviridae. It is an enveloped single-stranded positive …
Emerging role of IL-6 and NLRP3 inflammasome as potential therapeutic targets to combat COVID-19: Role of lncRNAs in cytokine storm modulation
A Paniri, H Akhavan-Niaki - Life sciences, 2020 - Elsevier
The world has witnessed a high morbidity and mortality caused by SARS-CoV-2, and global
death toll is still rising. Exaggerated inflammatory responses are thought to be more …
death toll is still rising. Exaggerated inflammatory responses are thought to be more …
Investigating the Nexus of NLRP3 Inflammasomes and COVID-19 Pathogenesis: Unraveling Molecular Triggers and Therapeutic Strategies
Q He, D Hu, F Zheng, W Chen, K Hu, J Liu, C Yao, H Li… - Viruses, 2024 - mdpi.com
The coronavirus disease 2019 (COVID-19) global pandemic, caused by severe acute
respiratory syndrome coronavirus type 2 (SARS-CoV-2), has been marked by severe cases …
respiratory syndrome coronavirus type 2 (SARS-CoV-2), has been marked by severe cases …
NLRP3, the inflammasome and COVID-19 infection
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by respiratory
failure, shock or multiorgan dysfunction, often accompanied by systemic hyperinflammation …
failure, shock or multiorgan dysfunction, often accompanied by systemic hyperinflammation …
NLRP3 and Infections: β-Amyloid in Inflammasome beyond Neurodegeneration
Amyloid beta (Aβ)-induced abnormal neuroinflammation is recognized as a major
pathological feature of Alzheimer's disease (AD), which results in memory impairment …
pathological feature of Alzheimer's disease (AD), which results in memory impairment …
Interleukin-1 and the NLRP3 inflammasome in COVID-19: Pathogenetic and therapeutic implications
A hyperinflammatory response during severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection crucially worsens clinical evolution of coronavirus disease 2019 …
(SARS-CoV-2) infection crucially worsens clinical evolution of coronavirus disease 2019 …