Anti-colon Cancer Effects of Dendrobium officinale Kimura & Migo Revealed by Network Pharmacology Integrated With Molecular Docking and Metabolomics Studies

S Tao, J Li, H Wang, S Ding, W Han, R He… - Frontiers in …, 2022 - frontiersin.org
Objective The present study aimed to investigate the potential mechanism of Dendrobium
officinale (D. officinale) on colorectal cancer and the relevant targets in the pathway using a …

Network Pharmacologic Analysis of Dendrobium officinale Extract Inhibiting the Proliferation of Gastric Cancer Cells

L Wei, W Dong, Z Han, C Chen, Q Jin, J He… - Frontiers in …, 2022 - frontiersin.org
Globally, gastric cancer (GC) is one of the three most deadly cancers. Dendrobium officinale
(D. officinale) is a traditional Chinese medicine (TCM), and its extract can significantly inhibit …

Integrated component identification, network pharmacology, and experimental verification revealed mechanism of Dendrobium officinale Kimura et Migo against lung …

Y Zhao, S Zhu, Y Li, X Niu, G Shang, X Zhou… - … of Pharmaceutical and …, 2024 - Elsevier
Abstract Background Dendrobium officinale Kimura et Migo (DO), a valuable Chinese herbal
medicine, has been reported to exhibit potential effects in the prevention and treatment of …

Integrated analysis of Dendrobium nobile extract Dendrobin A against pancreatic ductal adenocarcinoma based on network pharmacology, bioinformatics, and …

X Xu, Y Yu, L Yang, B Wang, Y Fan, B Ruan… - Frontiers in …, 2023 - frontiersin.org
Background: Dendrobium nobile (D. nobile), a traditional Chinese medicine, has received
attention as an anti-tumor drug, but its mechanism is still unclear. In this study, we applied …

Erianin, the main active ingredient of Dendrobium chrysotoxum Lindl, inhibits precancerous lesions of gastric cancer (PLGC) through suppression of the HRAS-PI3K …

Y Wang, F Chu, J Lin, Y Li, N Johnson, J Zhang… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Dendrobium chrysotoxum Lindl, a well-known
traditional Chinese medicinal herb used in the treatment of gastric disease, is distinguished …

Identification of the active substances and mechanisms of ginger for the treatment of colon cancer based on network pharmacology and molecular docking

MM Zhang, D Wang, F Lu, R Zhao, X Ye, L He, L Ai… - BioData mining, 2021 - Springer
Background and objective Colon cancer is occurring at an increasing rate and ginger
(Zingiber officinale), as a commonly used herbal medicine, has been suggested as a …

Molecular targets of Chinese herbs: a clinical study of metastatic colorectal cancer based on network pharmacology

H Zhu, J Hao, Y Niu, D Liu, D Chen, X Wu - Scientific reports, 2018 - nature.com
Increasing evidence has shown that Chinese herbal medicine (CHM) has promising
therapeutic effects in colorectal cancer (CRC); however, the active ingredients and potential …

Danggui buxue decoction in the treatment of metastatic colon cancer: network pharmacology analysis and experimental validation

SH Feng, B Zhao, X Zhan, R Motanyane… - Drug design …, 2021 - Taylor & Francis
Purpose This study aimed to reveal Danggui Buxue Decoction (DBD) candidate targets and
mechanisms in the treatment of metastatic colon cancer (MCC), using network …

[HTML][HTML] Network pharmacology prediction and molecular docking-based strategy to discover the potential pharmacological mechanism of action of Wang Bu Liu Xing …

Y Shi, Y Zhang, J Liu, Y Zhao, W Liu - Journal of Gastrointestinal …, 2023 - ncbi.nlm.nih.gov
Background Colorectal cancer (CRC) is the leading cause of cancer-related death
worldwide. Wang Bu Liu Xing [Semen vaccariae (SV)] is a traditional Chinese medicine …

A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer

X Liu, J Wu, D Zhang, K Wang, X Duan… - Evidence‐Based …, 2018 - Wiley Online Library
Background. As one of the most frequently diagnosed cancer diseases globally, colorectal
cancer (CRC) remains an important cause of cancer‐related death. Although the traditional …