The aim of this work was to be combine two pharmocophoric nuclei viz, triazole and
chalcone and evaluate their antitubercular activity. Propargylated vanillin was condensed …

Two novel series comprising of forty two compounds have been synthesized by conjugating
quinoline scaffold with chalcone as well as pyrazoline motifs. All the synthesized conjugates …

The synthesis of a new series of triazole-biscoumarin conjugates by using a molecular
hybridization approach is described. The newly synthesized compounds 6a–k were …

In this work, we report a series of 4-(2, 6-dimethylphenyl) thio) methyl)-2H-chromen-2-one
conjugates as promising leads to treat tuberculosis. Spectroscopic and other analytical …

The condensation of propargylated vanillin with differently substituted acetophenones
produced the corresponding chalcones which were reacted with substituted benzyl azides …

Using novel hybrid molecules for the treatment of tuberculosis is one of the latest
approaches. Keeping this concept in mind, thirty two hybrid compounds were synthesized …

Pyrazole, coumarin, and quinoline are medicinally important moieties. In this study, two
series of novel pyrazole–coumarin chalcones and pyrazole–quinoline chalcones were …

Pyrazolines are well known and important nitrogen containing 5-membered heterocyclic
compounds could effective against diversity of biological issue in which the tuberculosis is …

A very interesting foundation for this study is the creation of new methods for modifying
compounds with a 1, 2, 3‐triazole and chalcone scaffolds, as these compounds are …

Compounds bearing thiazole and chalcone pharmacophores have been reported to
possess excellent antitubercular and anticancer activities. In view of this, we designed …