The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …

Advances in the research of mechanism and related immunotherapy on the cytokine storm induced by coronavirus disease 2019

C Chen, XR Zhang, ZY Ju, WF He - Zhonghua shao shang za zhi …, 2020 - europepmc.org
Coronavirus disease 2019 (COVID-19) has seriously affected the safety of patients and
social stability. Some COVID-19 patients in the later stage of disease may develop into acute …

Innate immunological pathways in COVID-19 pathogenesis

SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound
dysregulation of the innate immune system. This knowledge has emerged from the large …

Dysregulation of the immune response in coronavirus disease 2019

L Mohamed Khosroshahi, N Rezaei - Cell Biology International, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can trigger a cytokine
storm in the pulmonary tissue by releasing various types of mediators, leading to acute …

Pathogenic T-cells and inflammatory monocytes incite inflammatory storms in severe COVID-19 patients

Y Zhou, B Fu, X Zheng, D Wang, C Zhao… - National Science …, 2020 - academic.oup.com
Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV
(SARS-CoV) and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …

Therapeutic approaches for COVID-19 based on the dynamics of interferon-mediated immune responses

P Mosaddeghi, M Negahdaripour, Z Dehghani… - 2020 - preprints.org
As the outbreak of COVID-19 has accelerated, an urgent need for finding strategies to
combat the virus is growing. Thus, gaining more knowledge on the pathogenicity …

Immune dysregulation and system pathology in COVID-19

M Jamal, HI Bangash, M Habiba, Y Lei, T Xie, J Sun… - Virulence, 2021 - Taylor & Francis
ABSTRACT The coronavirus disease 19 (COVID-19) caused by the novel coronavirus
known as SARS-CoV-2 has caused a global public health crisis. As of 7 January 2021 …

Hyperinflammatory response in COVID-19: a systematic review

MJA Silva, LR Ribeiro, MIM Gouveia, BR Marcelino… - Viruses, 2023 - mdpi.com
COVID-19 is a multisystemic disease caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The immunopathogenic conditions of the hyperinflammatory …

Advances in the research of cytokine storm mechanism induced by Corona Virus Disease 2019 and the corresponding immunotherapies

C Chen, X ZHANG, Z JU, W HE - Chinese journal of burns, 2020 - pesquisa.bvsalud.org
ABSTRACT Corona Virus Disease 2019 (COVID-19) has seriously affected the treatment of
patients and social stability. In the later stage of disease, some COVID-19 patients may …

Immune response in COVID-19: what is next?

Q Li, Y Wang, Q Sun, J Knopf, M Herrmann… - Cell Death & …, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) has been a global pandemic for more
than 2 years and it still impacts our daily lifestyle and quality in unprecedented ways. A …