Viruses with negative-strand RNA genomes (NSVs) include many highly pathogenic and
economically devastating disease-causing agents of humans, livestock, and plants …

The nonsegmented, negative-strand RNA viruses (nsNSVs), also known as the order
Mononegavirales, have a genome consisting of a single strand of negative-sense RNA …

Mononegavirales, known as nonsegmented negative-sense (NNS) RNA viruses, are a class
of pathogenic and sometimes deadly viruses that include rabies virus (RABV), human …

RNA viruses include many important human and animal pathogens, such as the influenza
viruses, respiratory syncytial virus, Ebola virus, measles virus and rabies virus. The …

Highlights•Crystal and cryo-EM structures of NSV polymerases influenza, La Crosse and
VSV.•Segmented and non-segmented NSV polymerases have a similar extended core …

Negative-strand (NS) RNA viruses initiate infection with a unique polymerase complex that
mediates both mRNA transcription and subsequent genomic RNA replication. For nearly all …

All enzymatic activities required for genomic replication and transcription of nonsegmented
negative strand RNA viruses (or Mononegavirales) are believed to be concentrated in the …

Non-segmented negative strand (NNS) RNA viruses belonging to the order
Mononegavirales are highly diversified eukaryotic viruses including significant human …

Segmented negative-strand RNA virus (sNSV) polymerases transcribe and replicate the
viral RNA (vRNA) within a ribonucleoprotein particle (RNP). We present cryo-EM and X-ray …

Most emerging and re-emerging human and animal viral diseases are associated with RNA
viruses. All these pathogens, with the exception of retroviruses, encode a specialized …