A series of primaquine analogs was prepared, according to a conformationally restricted
conformation of primaquine. In vitro antiplasmodial activities were evaluated and showed …

A series of flavone-stilbene-based hybrid molecules were synthesized in good to excellent
yield (65–95%) via Heck coupling as the key step under conventional as well as microwave …

In the present study, a series of forty-five asymmetrical meta-methoxylated diarylpentanoids
have been synthesized, characterized and evaluated for their in-vitro anti-cancer potential …

In our continuing work looking for new anti-infective lead compounds from Brazilian biomes,
the two known piperidine alkaloids (-)-cassine and (-)-spectaline were isolated from the …

Long-term use of approved antiviral drugs can lead to drug resistance and side effects. On
the other hand, there are currently no antiviral drugs or vaccines available to treat some …

The molecular modelling approach was applied to a series of nineteen curcumin analogues
to find the possible PfRIO2 kinase inhibitory action. A putative active site in flexible loop (S1) …

Summary Malaria, human African trypanosomiasis, Chagas and leishmaniasis are four
protozoan tropical infectious diseases that remain a global public health problem with …

For reprint orders, please contact reprints@ future-science. com companies in recent years
is heartening because they have the majority of medicinal chemistry expertise at their …

Natural products are not only the basis for traditional or ethnic medicine. Only recently, they
have provided highly successful new drugs such as Artemisinin. Furthermore, screening …

Abstract β-Carboline alkaloids are an eminent class of nitrogen-based natural alkaloids and
therapeutic molecules which exert various pharmacological activities through diverse …