Acceptance, availability, and feasibility of RTS, S/AS01 malaria vaccine: a review

H Mumtaz, A Nadeem, W Bilal, F Ansar… - Immunity …, 2023 - Wiley Online Library
Introduction In malaria‐stricken regions, malaria continues to be one of the primary causes
of mortality for children. The number of malaria‐related fatalities has drastically decreased …

Acceptance, availability and feasibility of RTS, S/AS01 malaria vaccine: a review of literature

A Nadeem, W Bilal - Asian Pacific Journal of Tropical Medicine, 2023 - journals.lww.com
Malaria remains the most serious infectious disease and is one of the leading causes of
death among children in malaria endemic areas. The development of malaria vaccines has …

Unlocking the potential of novel RTS, S/AS01, and R21/Matrix‐M™ malaria vaccines in African nations

MO Oduoye, MU Haider, MDM Marsool… - Health Science …, 2024 - Wiley Online Library
Introduction Mass malaria vaccination, rather than vaccinating only children below age 5,
has been proven to have the potential to reduce morbidity and mortality among those …

Assessing the safety, impact and effectiveness of RTS,S/AS01E malaria vaccine following its introduction in three sub-Saharan African countries: methodological …

N Praet, KP Asante, MC Bozonnat, EJ Akité, PO Ansah… - Malaria Journal, 2022 - Springer
Background Following a 30-year development process, RTS, S/AS01E (GSK, Belgium) is
the first malaria vaccine to reach Phase IV assessments. The World Health Organization …

Current challenges and proposed solutions to the effective implementation of the RTS, S/AS01 Malaria Vaccine Program in sub-Saharan Africa: A systematic review

CA Dimala, BT Kika, BM Kadia, H Blencowe - PloS one, 2018 - journals.plos.org
Background The Malaria Vaccine Implementation Program, coordinated by the World Health
Organization, intended to initiate the roll-out of the RTS, S/AS01 malaria vaccine in 3 sub …

Safety of the Malaria Vaccine Candidate, RTS,S/AS01E in 5 to 17 Month Old Kenyan and Tanzanian Children

J Lusingu, A Olotu, A Leach, M Lievens, J Vekemans… - PLoS …, 2010 - journals.plos.org
The malaria vaccine candidate, RTS, S/AS01E, showed promising protective efficacy in a
trial of Kenyan and Tanzanian children aged 5 to 17 months. Here we report on the …

Clinical development of RTS, S/AS malaria vaccine: a systematic review of clinical Phase I–III trials

ST Agnandji, JF Fernandes, EB Bache… - Future …, 2015 - Taylor & Francis
The first clinical Phase III trial evaluating a malaria vaccine was completed in December
2013 at 11 sites from seven sub-Saharan African countries. This systematic review assesses …

Design of a phase III multicenter trial to evaluate the efficacy of the RTS, S/AS01 malaria vaccine in children across diverse transmission settings in Africa

A Leach, J Vekemans, M Lievens, O Ofori-Anyinam… - Malaria journal, 2011 - Springer
Abstract Background GlaxoSmithKline Biologicals and the PATH Malaria Vaccine Initiative
are working in partnership to develop a malaria vaccine to protect infants and children living …

Safety and immunogenicity of the RTS, S/AS02A candidate malaria vaccine in children aged 1–4 in Mozambique

E Macete, JJ Aponte, C Guinovart… - Tropical Medicine & …, 2007 - Wiley Online Library
Background The development of a malaria vaccine remains a public health priority for sub‐
Saharan Africa. RTS, S/AS02A candidate malaria vaccine has been shown to be safe and …

Malaria vaccines: the 60-year journey of hope and final success—lessons learned and future prospects

AA El-Moamly, MA El-Sweify - Tropical Medicine and Health, 2023 - Springer
Background The world has made great strides towards beating malaria, although about half
of the world population is still exposed to the risk of contracting malaria. Developing an …