Malaria vaccine efficacy, safety, and community perception in Africa: a scoping review of recent empirical studies

M Chutiyami, P Saravanakumar, UM Bello, D Salihu… - Infection, 2024 - Springer
Aim The review summarizes the recent empirical evidence on the efficacy, safety, and
community perception of malaria vaccines in Africa. Methods Academic Search Complete …

Seven-year efficacy of RTS, S/AS01 malaria vaccine among young African children

A Olotu, G Fegan, J Wambua… - … England Journal of …, 2016 - Mass Medical Soc
Background The candidate malaria vaccine RTS, S/AS01 is being evaluated in order to
inform a decision regarding its inclusion in routine vaccination schedules. Methods We …

The RTS, S vaccine candidate for malaria

JA Regules, JF Cummings… - Expert review of …, 2011 - Taylor & Francis
Malaria continues to be a worldwide leading cause of morbidity and mortality, and the
development of an effective malaria vaccine remains a research imperative. Of the multiple …

Randomized, controlled trial of the long term safety, immunogenicity and efficacy of RTS,S/AS02D malaria vaccine in infants living in a malaria-endemic region

S Abdulla, N Salim, F Machera, R Kamata, O Juma… - Malaria journal, 2013 - Springer
Abstract Background The RTS, S/AS malaria candidate vaccine is being developed with the
intent to be delivered, if approved, through the Expanded Programme on Immunization (EPI) …

A malaria vaccine for Africa—an important step in a century-long quest

PL Alonso, KL O'Brien - New England Journal of Medicine, 2022 - Mass Medical Soc
A Malaria Vaccine for Africa — An Important Step in a Century-Long Quest | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Evaluation of RTS, S/AS02A and RTS, S/AS01B in adults in a high malaria transmission area

ME Polhemus, SA Remich, BR Ogutu, JN Waitumbi… - PloS one, 2009 - journals.plos.org
Background This study advances the clinical development of the RTS, S/AS01B candidate
malaria vaccine to malaria endemic populations. As a primary objective it compares the …

Randomized Controlled Trial of RTS,S/AS02D and RTS,S/AS01E Malaria Candidate Vaccines Given According to Different Schedules in Ghanaian Children

S Owusu-Agyei, D Ansong, K Asante… - PLoS …, 2009 - journals.plos.org
Background The target delivery channel of RTS, S candidate malaria vaccines in malaria-
endemic countries in Africa is the World Health Organisation Expanded Program on …

Combining antimalarial drugs and vaccine for malaria elimination campaigns: a randomized safety and immunogenicity trial of RTS, S/AS01 administered with …

L von Seidlein, B Hanboonkunupakarn… - Human Vaccines & …, 2020 - Taylor & Francis
ABSTRACT Introduction: RTS, S/AS01 is currently the most advanced malaria vaccine but
provides incomplete, short-term protection. It was developed for use within the expanded …

The RTS, S/AS01 malaria vaccine in children 5 to 17 months of age at first vaccination

P Vandoolaeghe, L Schuerman - Expert review of vaccines, 2016 - Taylor & Francis
ABSTRACT The RTS, S/AS01 malaria vaccine received a positive scientific opinion from the
European Medicines Agency in July 2015. The World Health Organization recommended …

The RTS, S malaria vaccine

S Casares, TD Brumeanu, TL Richie - Vaccine, 2010 - Elsevier
RTS, S is the most advanced candidate vaccine against human malaria. During its
remarkable journey from conception and design in the early 1980s to the multicenter Phase …