HIF-1α promotes SARS-CoV-2 infection and aggravates inflammatory responses to COVID-19
M Tian, W Liu, X Li, P Zhao, MA Shereen… - … and Targeted Therapy, 2021 - nature.com
Cytokine storm induced by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-
2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial …
2) is a major pathological feature of Coronavirus Disease 2019 (COVID-19) and a crucial …
Ubiquitination of SARS-CoV-2 ORF7a promotes antagonism of interferon response
Z Cao, H Xia, R Rajsbaum, X Xia, H Wang… - Cellular & molecular …, 2021 - nature.com
Understanding interactions between the host and SARS-CoV-2 is essential for developing
effective vaccines and therapeutics. Here, we report that SARS-CoV-2 usurps the host …
effective vaccines and therapeutics. Here, we report that SARS-CoV-2 usurps the host …
Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes
Z Zhou, C Huang, Z Zhou, Z Huang, L Su, S Kang… - IScience, 2021 - cell.com
Dysregulated immune cell responses have been linked to the severity of coronavirus
disease 2019 (COVID-19), but the specific viral factors of severe acute respiratory syndrome …
disease 2019 (COVID-19), but the specific viral factors of severe acute respiratory syndrome …
SARS‐CoV‐2 ORF9b antagonizes type I and III interferons by targeting multiple components of the RIG‐I/MDA‐5–MAVS, TLR3–TRIF, and cGAS–STING signaling …
L Han, MW Zhuang, J Deng, Y Zheng… - Journal of medical …, 2021 - Wiley Online Library
The suppression of types I and III interferon (IFN) responses by severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) contributes to the pathogenesis of coronavirus …
syndrome coronavirus 2 (SARS‐CoV‐2) contributes to the pathogenesis of coronavirus …
SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70
H Jiang, H Zhang, Q Meng, J Xie, Y Li… - Cellular & molecular …, 2020 - nature.com
COVID-19 is caused by SARS-CoV-2. 1 As of July 16th, 2020, there were 13,579,581
diagnosed cases and 584,782 deaths attributed to COVID-19 reported globally …
diagnosed cases and 584,782 deaths attributed to COVID-19 reported globally …
[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19
JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …
SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy
X Li, P Hou, W Ma, X Wang, H Wang, Z Yu… - Cellular & molecular …, 2022 - nature.com
The global coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused severe morbidity and …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused severe morbidity and …
Inflammatory cytokine: IL-17A signaling pathway in patients present with COVID-19 and current treatment strategy
T Shibabaw - Journal of inflammation research, 2020 - Taylor & Francis
Abstract Coronavirus disease 2019 (COVID-19) is a globally communicable public health
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV-2) …
disease caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV-2) …
SARS-CoV-2 ORF8 protein induces endoplasmic reticulum stress-like responses and facilitates virus replication by triggering calnexin: an unbiased study
X Wang, W Wang, T Wang, J Wang, Y Jiang… - Journal of …, 2023 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen
responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic. The novel …
responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic. The novel …
Ubiquitination of SARS-CoV-2 NSP6 and ORF7a facilitates NF-κB activation
H Nishitsuji, S Iwahori, M Ohmori, K Shimotohno… - MBio, 2022 - Am Soc Microbiol
Patients with severe coronavirus disease 2019 tend to have high levels of proinflammatory
cytokines, which eventually lead to cytokine storm and the development of acute respiratory …
cytokines, which eventually lead to cytokine storm and the development of acute respiratory …