An efficient strategy for viruses to take over infected cells and evade the antiviral response is
to block host gene expression, a process termed host shutoff. Influenza A virus carries out …

To counteract host antiviral responses, influenza A virus triggers a global reduction of
cellular gene expression, a process termed “host shutoff.” A key effector of influenza A virus …

To counteract host antiviral responses, influenza A virus triggers a global reduction of
cellular gene expression, a process termed “host shutoff.” A key effector of influenza A virus …

Many viruses shut off host gene expression to inhibit antiviral responses. Viral proteins and
host proteins required for viral replication are typically spared in this process, but the …

Widespread shutoff of host gene expression through RNA degradation is an advantageous
way for many viruses to block antiviral responses. However, viruses need to maintain …

Many viruses block host gene expression to take over the infected cell. This process, termed
host shutoff, is thought to promote viral replication by preventing antiviral responses and …

Influenza virus infection causes global inhibition of host protein synthesis in infected cells.
This host shutoff is thought to allow viruses to escape from the host antiviral response, which …

ABSTRACT PA-X is a recently identified influenza virus protein that is composed of the PA N-
terminal 191 amino acids and unique C-terminal 41 or 61 residues. We and others showed …

The influenza A endoribonuclease (RNase) PA-X regulates virulence and transmission of
the virus by suppressing host gene expression and thus inhibiting the antiviral response …

The influenza A endoribonuclease PA-X regulates virulence and transmission of the virus by
reducing host gene expression and thus regulating immune responses to influenza A virus …