The Jun and Fos oncoproteins belong to the AP-1 family of transcriptional activators and are
believed to induce cellular transformation by inappropriately activating genes involved in …

The AP-1 transcription factor is composed of a mixture of homo-and hetero-dimers formed
between Jun and Fos proteins. The different Jun and Fos family members vary significantly …

Oncogene research has led to the isolation of specific reagents that have allowed important
insights in several disciplines. Recently, studies on oncogenes encoding nuclear proteins …

Jun and Fos proteins are DNA-binding proteins that are involved in the control of gene
expression through transcriptional regulation. We have made a deletion mutant of the c-jun …

Transcription factor AP-1 is constituted by the products of the various fos and jun genes. AP-
1 activity is modulated by second messengers and appears to involve post-translational …

The proto-oncogenes jun and fos are members of the AP-1 family of transcription factors,
which activate transcription of target genes via the tetradecanoyl phorbol acetate response …

The nuclear phosphoprotein c-Jun, encoded by the proto-oncogene c-jun, is a major
component of the AP-1 complex. A potent transcriptional regulator, c-jun is also able to …

the ability to cause cancersas a result. The namefos, for example, reflects the identification of
this oncogene in the FBJ and FBR osteogenic sarcoma viruses. Under normal …

ras is an important oncogene in experimental animals and humans. In addition, activated ras
proteins are potent inducers of the transcription factor AP-1, which is composed of …

RECENT advances indicate a link between tumour promoters, transformation, and AP-1
activity1. Protein kinase C activation increases AP-1 DNA-binding activity independently of …