Rationale for a multi-factorial approach for the reversal of cognitive decline in Alzheimer's disease and MCI: a review

RV Rao, KG Subramaniam, J Gregory… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative disease
typically characterized by memory loss, personality changes, and a decline in overall …

Lifestyle modifications and nutritional interventions in aging-associated cognitive decline and Alzheimer's disease

GK Bhatti, AP Reddy, PH Reddy… - Frontiers in aging …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a type of incurable neurodegenerative disease that is
characterized by the accumulation of amyloid-β (Aβ; plaques) and tau hyperphosphorylation …

Insights into the pathophysiology of Alzheimer's disease and potential therapeutic targets: A current perspective

K Rajah Kumaran, S Yunusa, E Perimal… - Journal of …, 2023 - content.iospress.com
The aging population increases steadily because of a healthy lifestyle and medical
advancements in healthcare. However, Alzheimer's disease (AD) is becoming more …

Alzheimer's disease—Biochemical and psychological background for diagnosis and treatment

BK Beata, J Wojciech, K Johannes, L Piotr… - International journal of …, 2023 - mdpi.com
There is a paucity of empirical research on the use of non-pharmacological interventions to
both treat and curb the spread of Alzheimer's disease (AD) across the globe. This paper …

Lifestyle strategies to promote proteostasis and reduce the risk of Alzheimer's disease and other proteinopathies

MF Almeida, KLG Farizatto, RS Almeida… - Ageing Research …, 2023 - Elsevier
Unhealthy lifestyle choices, poor diet, and aging can have negative influences on cognition,
gradually increasing the risk for mild cognitive impairment (MCI) and the continuum …

Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease

V Frisardi, V Solfrizzi, D Seripa, C Capurso… - Ageing research …, 2010 - Elsevier
A growing body of epidemiological evidence suggested that metabolic syndrome (MetS) and
Mets components (impaired glucose tolerance, abdominal or central obesity, hypertension …

Current concepts of neurodegenerative mechanisms in Alzheimer's disease

KB Magalingam, A Radhakrishnan… - BioMed research …, 2018 - Wiley Online Library
Neurodegenerative diseases are hereditary or sporadic conditions that result in the
progressive loss of the structure and function of neurons as well as neuronal death …

The role of selected bioactive compounds in the prevention of Alzheimer's disease

W Grodzicki, K Dziendzikowska - Antioxidants, 2020 - mdpi.com
Neurodegeneration is a feature of many debilitating, incurable age-dependent diseases that
affect the nervous system and represent a major threat to the health of elderly persons …

Mechanisms of risk reduction in the clinical practice of Alzheimer's disease prevention

MW Schelke, P Attia, DJ Palenchar… - Frontiers in aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is a neurodegenerative dementia that affects nearly 50 million
people worldwide and is a major source of morbidity, mortality, and healthcare expenditure …

Diet and lifestyle impact the development and progression of Alzheimer's dementia

S Arora, JA Santiago, M Bernstein… - Frontiers in Nutrition, 2023 - frontiersin.org
Dementia is a growing public health concern, with an estimated prevalence of 57 million
adults worldwide. Alzheimer's disease (AD) accounts for 60–80% of the cases. Clinical trials …