[HTML][HTML] Accurate brain‐age models for routine clinical MRI examinations

DA Wood, S Kafiabadi, A Al Busaidi, E Guilhem… - Neuroimage, 2022 - Elsevier
Convolutional neural networks (CNN) can accurately predict chronological age in healthy
individuals from structural MRI brain scans. Potentially, these models could be applied …

Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker

JH Cole, RPK Poudel, D Tsagkrasoulis, MWA Caan… - NeuroImage, 2017 - Elsevier
Abstract Machine learning analysis of neuroimaging data can accurately predict
chronological age in healthy people. Deviations from healthy brain ageing have been …

[HTML][HTML] Learning patterns of the ageing brain in MRI using deep convolutional networks

NK Dinsdale, E Bluemke, SM Smith, Z Arya, D Vidaurre… - NeuroImage, 2021 - Elsevier
Both normal ageing and neurodegenerative diseases cause morphological changes to the
brain. Age-related brain changes are subtle, nonlinear, and spatially and temporally …

Estimating brain age based on a uniform healthy population with deep learning and structural magnetic resonance imaging

X Feng, ZC Lipton, J Yang, SA Small… - Neurobiology of …, 2020 - Elsevier
Numerous studies have established that estimated brain age constitutes a valuable
biomarker that is predictive of cognitive decline and various neurological diseases. In this …

MRI signatures of brain age and disease over the lifespan based on a deep brain network and 14 468 individuals worldwide

VM Bashyam, G Erus, J Doshi, M Habes, IM Nasrallah… - Brain, 2020 - academic.oup.com
Deep learning has emerged as a powerful approach to constructing imaging signatures of
normal brain ageing as well as of various neuropathological processes associated with …

Benchmarking the generalizability of brain age models: Challenges posed by scanner variance and prediction bias

RJ Jirsaraie, T Kaufmann, V Bashyam… - Human Brain …, 2023 - Wiley Online Library
Abstract Machine learning has been increasingly applied to neuroimaging data to predict
age, deriving a personalized biomarker with potential clinical applications. The scientific and …

Anatomically interpretable deep learning of brain age captures domain-specific cognitive impairment

C Yin, P Imms, M Cheng, A Amgalan… - Proceedings of the …, 2023 - National Acad Sciences
The gap between chronological age (CA) and biological brain age, as estimated from
magnetic resonance images (MRIs), reflects how individual patterns of neuroanatomic aging …

[HTML][HTML] Deep neural networks learn general and clinically relevant representations of the ageing brain

EH Leonardsen, H Peng, T Kaufmann, I Agartz… - NeuroImage, 2022 - Elsevier
The discrepancy between chronological age and the apparent age of the brain based on
neuroimaging data—the brain age delta—has emerged as a reliable marker of brain health …

Machine learning for brain age prediction: Introduction to methods and clinical applications

L Baecker, R Garcia-Dias, S Vieira, C Scarpazza… - …, 2021 - thelancet.com
The rise of machine learning has unlocked new ways of analysing structural neuroimaging
data, including brain age prediction. In this state-of-the-art review, we provide an …

Prediction of brain age using structural magnetic resonance imaging: A comparison of accuracy and test–retest reliability of publicly available software packages

RP Dörfel, JM Arenas‐Gomez, PM Fisher… - Human Brain …, 2023 - Wiley Online Library
Brain age prediction algorithms using structural magnetic resonance imaging (MRI) aim to
assess the biological age of the human brain. The difference between a person's …