Aging as an irretrievable occurrence throughout the entire life is characterized by a
progressive decline in physiological functionality and enhanced disease vulnerability …

Aging is a multifactorial process characterized by the progressive loss of physiological
functions, leading to an increased vulnerability to age‐associated diseases and finally to …

Background Multiple processes have been implicated in age-related delayed healing,
including altered gene expression, intrinsic cellular changes, and changes in extracellular …

Aging is the single most important risk factor for diseases that are currently the leading
causes of morbidity and mortality. However, there is considerable inter-individual variability …

Epigenetics refers to phenotypic changes caused by mechanisms that are unrelated to
changes in the underlying DNA sequence, most notably chromatin remodeling driven by …

Aging is a pleiotropic process affecting many aspects of mammalian physiology. Mammals
are composed of distinct cell type identities and tissue environments, but the influence of …

Aging is the most important risk factor for major human lifestyle diseases, including cancer,
neurological and cardiometabolic disorders. Due to the complex interplay between genetics …

Multiple studies characterizing the human ageing phenotype have been conducted for
decades. However, there is no centralized resource in which data on multiple age-related …

Aging inevitably leads to reduced immune function, leaving the elderly more susceptible to
infections, less able to respond to pathogen challenges, and less responsive to preventative …

Ageing is a complex, multifaceted process leading to widespread functional decline that
affects every organ and tissue, but it remains unknown whether ageing has a unifying causal …