The field of genetics has expanded a lot in the past few decades due to the accessibility of
human genome sequences, but still, the regulation of transcription cannot be explicated …

Although the field of genetics has grown by leaps and bounds within the last decade due to
the completion and availability of the human genome sequence, transcriptional regulation …

DNA methylation is commonly associated with gene silencing, and a link between histone
deacetylation and DNA methylation has been established. However, the transcriptional …

Accumulating evidence has revealed that epigenetics is critical in understanding the basic
molecular mechanisms that take place in chromatin (transcription, splicing, replication and …

Epigenetic regulation is the mechanism by which gene function is selectively activated or
inactivated in the cells. It provides higher-ordered and more specified genetic information …

Epigenetics is the study of heritable and stable changes in gene expression that occur
through alterations in the chromosome rather than in the DNA sequence. Despite not directly …

DNA methylation is important in the control of gene transcription and chromatin structure.
The complexities of this process are just beginning to be elucidated in relationship to other …

It is still not clear how eukaryotic cells regulate gene expression during differentiation and in
the differentiated state. There is increasing experimental evidence that this requires a wide …

Over the past year or so, methylation of histones has come to be recognised as a major
player in the regulation of gene activity. This notion follows the discovery of lysine and …

One of the most fundamental questions in the control of gene expression in mammals is how
epigenetic methylation patterns of DNA and histones are established, erased, and …