Are highly stable covalent organic frameworks the key to universal chiral stationary phases for liquid and gas chromatographic separations?

C Yuan, W Jia, Z Yu, Y Li, M Zi… - Journal of the American …, 2022 - ACS Publications
High-performance liquid chromatography (HPLC) and gas chromatography (GC) over chiral
stationary phases (CSPs) represent the most popular and highly applicable technology in …

Chiral 3D covalent organic frameworks for high performance liquid chromatographic enantioseparation

X Han, J Huang, C Yuan, Y Liu… - Journal of the American …, 2018 - ACS Publications
In spite of their great promise for enantioselective processes due to the rich host–guest
chemistry, it remains a challenge to construct covalent organic frameworks (COFs) with …

Cyclodextrin incorporation into covalent organic frameworks enables extensive liquid and gas chromatographic enantioseparations

C Yuan, Z Wang, W Xiong, Z Huang, Y Lai… - Journal of the …, 2023 - ACS Publications
The separation of enantiomers using high-performance chromatography technologies
represents great importance and interest. In this aspect, β-cyclodextrin (β-CD) and its …

Bottom-up synthesis of chiral covalent organic frameworks and their bound capillaries for chiral separation

HL Qian, CX Yang, XP Yan - Nature communications, 2016 - nature.com
Covalent organic frameworks (COFs) are a novel class of porous materials, and offer great
potential for various applications. However, the applications of COFs in chiral separation …

“Thiol–ene” click synthesis of chiral covalent organic frameworks for gas chromatography

JX Guo, C Yang, XP Yan - Journal of Materials Chemistry A, 2021 - pubs.rsc.org
The unique properties of covalent organic frameworks (COFs), such as a large specific
surface area, good stability and easy functionalization, make them have good potential in …

A β-cyclodextrin covalent organic framework used as a chiral stationary phase for chiral separation in gas chromatography

B Tang, W Wang, H Hou, Y Liu, Z Liu, L Geng… - Chinese Chemical …, 2022 - Elsevier
Chiral covalent organic frameworks (CCOFs) featuring chirality, stability, and good porosity
have attracted a considerable amount of attention due to their important applications, such …

Construction of a hydrazone-linked chiral covalent organic framework–silica composite as the stationary phase for high performance liquid chromatography

K Zhang, SL Cai, YL Yan, ZH He, HM Lin… - … of Chromatography A, 2017 - Elsevier
Covalent organic frameworks (COFs), as an emerging class of crystalline porous organic
polymers, have great potential for applications in chromatographic separation owning to …

Highly stable Zr (IV)-based metal–organic frameworks for chiral separation in reversed-phase liquid chromatography

H Jiang, K Yang, X Zhao, W Zhang, Y Liu… - Journal of the …, 2020 - ACS Publications
Separation of racemic mixtures is of great importance and interest in chemistry and
pharmacology. Porous materials including metal–organic frameworks (MOFs) have been …

Covalent organic frameworks with chirality enriched by biomolecules for efficient chiral separation

S Zhang, Y Zheng, H An, B Aguila… - Angewandte Chemie …, 2018 - Wiley Online Library
The separation of racemic compounds is important in many fields, such as pharmacology
and biology. Taking advantage of the intrinsically strong chiral environment and specific …

Single-crystalline covalent organic frameworks as high-performance liquid chromatographic stationary phases for positional isomer separation

Q Zheng, J Huang, Y He, H Huang, Y Ji… - … Applied Materials & …, 2022 - ACS Publications
Vigorously developing new stationary phases to meet the requirements for the separation of
positional isomers that have similar physicochemical properties is still an urgent topic in …