The sweet side of wound healing: galectins as promising therapeutic targets in hemostasis, inflammation, proliferation, and maturation/remodeling

M Čoma, JC Manning, H Kaltner… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Understanding the molecular and cellular processes involved in skin wound
healing may pave the way for the development of innovative approaches to transforming the …

Human galectin‑3: Molecular switch of gene expression in dermal fibroblasts in vitro and of skin collagen organization in open wounds and tensile strength in incisions …

PT GÁl, T VaSilenKo, I Kováč… - Molecular …, 2021 - spandidos-publications.com
Understanding the molecular and cellular processes in skin wound healing can pave the
way for devising innovative concepts by turning the identified natural effectors into …

Role of galectins in wound healing

N Panjwani - Galectins and disease implications for targeted …, 2012 - ACS Publications
Impaired or delayed re-epithelialization underlies serious disorders of wound healing that
are painful, difficult to treat, and affect a variety of human tissues. Recent studies have …

Regulation of wound healing and fibrosis by galectins

D Yu, M Bu, P Yu, Y Li, Y Chong - Journal of Molecular Medicine, 2022 - Springer
Galectins are a family of proteins with at least one carbohydrate-recognition domain.
Galectins are present in various tissues and organs and participate in different physiological …

[HTML][HTML] Role of galectins in re-epithelialization of wounds

N Panjwani - Annals of translational medicine, 2014 - ncbi.nlm.nih.gov
Re-epithelialization is a critical contributing process in wound healing in the human body.
When this process is compromised, impaired or delayed, serious disorders of wound …

Galectin-3 regulation of wound healing and fibrotic processes: insights for chronic skin wound therapeutics

K McLeod, JT Walker, DW Hamilton - Journal of cell communication and …, 2018 - Springer
A member of the lectin family, galectin-3 is a 250 amino-acid protein that contains a C-
terminus carbohydrate recognition domain (CRD) that recognizes β-galactosides …

Open wound healing in vivo: Monitoring binding and presence of adhesion/growth-regulatory galectins in rat skin during the course of complete re-epithelialization

P Gál, T Vasilenko, M Kostelníková… - Acta Histochemica et …, 2011 - jstage.jst.go.jp
© 2011 The Japan Society of Histochemistry and Galectins are a family of carbohydrate-
binding proteins that modulate inflammation and immunity. This functional versatility …

Galectin 1—a key player between tissue repair and fibrosis

A Hermenean, D Oatis, H Herman, A Ciceu… - International journal of …, 2022 - mdpi.com
Galectins are ten family members of carbohydrate-binding proteins with a high affinity for β
galactose-containing oligosaccharides. Galectin-1 (Gal-1) is the first protein discovered in …

Galectin‐1 production is elevated in hypertrophic scar

LD Kirkpatrick, JW Shupp, RD Smith… - Wound Repair and …, 2021 - Wiley Online Library
Upon healing, burn wounds often leave hypertrophic scars (HTSs) marked by excess
collagen deposition, dermal and epidermal thickening, hypervascularity, and an increased …

The expression and function of galectins in skin physiology and pathology

NL Wu, FT Liu - Experimental Dermatology, 2018 - Wiley Online Library
The galectin family comprises β‐galactoside–binding proteins widely expressed in many
organisms. There are at least 16 family members, which can be classified into three groups …