Physical tuning of galectin-3 signaling

SA Farhadi, R Liu, MW Becker… - Proceedings of the …, 2021 - National Acad Sciences
Galectin-3 (Gal3) exhibits dynamic oligomerization and promiscuous binding, which can
lead to concomitant activation of synergistic, antagonistic, or noncooperative signaling …

The Sweet Kiss of Death A Link between Galectin-1, Glycosylation and the Generation of Immune Privilege

N Rubinstein, MA Toscano, JM Ilarregui… - … in Glycoscience and …, 2005 - jstage.jst.go.jp
抄録 よく保存された糖結合タンパク質ファミリーの一員であるガレクチン-1 (Gal-1) は,
強い免疫抑制性因子であり, かつ抗炎症因子であると報告されている. 目, 胎盤, 生殖器官 (精巣 …

Glycobiology simplified: diverse roles of glycan recognition in inflammation

RL Schnaar - Journal of Leucocyte Biology, 2016 - academic.oup.com
Glycans and complementary glycan-binding proteins are essential components in the
language of cell-cell interactions in immunity. The study of glycan function is the purview of …

Studies on immunological and degranulation properties of a galectin-1 purified from goat (Capra hircus) heart

GM Ashraf, MM Mahmoud, S Tabrez - International journal of biological …, 2018 - Elsevier
Galectins are mammalian lectins characterized by affinity for β-galactosides and the
presence of a conserved carbohydrate recognition domain (CRD). Galectins play crucial …

The Role of Plant Lectins in the Cellular and Molecular Processes of Skin Wound Repair: An Overview

G de Sousa, RG Lund… - Current Pharmaceutical …, 2023 - ingentaconnect.com
There is increasing pressure for innovative methods to treat compromised and difficult-to-
heal wounds. Consequently, new strategies are needed for faster healing, reducing …

Galectins in acute and chronic inflammation

FT Liu, RY Yang, DK Hsu - Annals of the New York Academy of …, 2012 - Wiley Online Library
Galectins are animal lectins that bind to β‐galactosides, such as lactose and N‐
acetyllactosamine, in free form or contained in glycoproteins or glycolipids. They are located …

Galectins: new agonists of platelet activation

M Schattner, GA Rabinovich - Biological chemistry, 2013 - degruyter.com
Platelet activation at sites of vascular injury leads to the formation of a hemostatic plug and is
crucial for hemostasis. However, uncontrolled platelet activation may lead to the formation of …

[PDF][PDF] Immunohistochemical Fingerprinting of the Network of Seven Adhe sion/Growth-Regulatory Lectins in Human Skin and De-tection of Distinct Tumour …

Z Čada, K Smetana Jr, L Lacina, Z Plzáková… - Folia Biologica …, 2009 - radio.lf1.cuni.cz
Glycans of natural glycoconjugates are considered as a source of biological information
relevant to cell adhesion or growth. Sugar-based messages are decoded and translated into …

Oligosaccharide ligands of galectin-4 and its subunits: multivalency scores highly

K Slámová, J Červený, Z Mészáros, T Friede, D Vrbata… - Molecules, 2023 - mdpi.com
Galectins are carbohydrate-binding lectins that modulate the proliferation, apoptosis,
adhesion, or migration of cells by cross-linking glycans on cell membranes or extracellular …

Studying the structural significance of galectin design by playing a modular puzzle: homodimer generation from human tandem-repeat-type (heterodimeric) galectin-8 …

AK Ludwig, M Michalak, N Shilova, S André, H Kaltner… - Molecules, 2017 - mdpi.com
Tissue lectins are emerging (patho) physiological effectors with broad significance. The
capacity of adhesion/growth-regulatory galectins to form functional complexes with distinct …