Surviving the storm: cytokine biosignature in SARS-CoV-2 severity prediction

R Ahmad, M Haque - Vaccines, 2022 - mdpi.com
Simple Summary The world has been stricken mentally, physically, and economically by the
COVID-19 virus. However, while SARS-CoV-2 viral infection results in mild flu-like symptoms …

Cytokine signature and COVID-19 prediction models in the two waves of pandemics

S Cabaro, V D'Esposito, T Di Matola, S Sale… - Scientific Reports, 2021 - nature.com
In Europe, multiple waves of infections with SARS-CoV-2 (COVID-19) have been observed.
Here, we have investigated whether common patterns of cytokines could be detected in …

The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2

S Muralidar, SV Ambi, S Sekaran, UM Krishnan - Biochimie, 2020 - Elsevier
An acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the …

Immune characterization and profiles of SARS-CoV-2 infected patients reveals potential host therapeutic targets and SARS-CoV-2 oncogenesis mechanism

M Policard, S Jain, S Rego, S Dakshanamurthy - Virus Research, 2021 - Elsevier
The spread of SARS-CoV-2 and the increasing mortality rates of COVID-19 create an urgent
need for treatments, which are currently lacking. Although vaccines have been approved by …

The many faces of innate immunity in SARS-CoV-2 infection

N Hanan, RL Doud Jr, IW Park, HP Jones, SO Mathew - Vaccines, 2021 - mdpi.com
The innate immune system is important for initial antiviral response. SARS-CoV-2 can result
in overactivity or suppression of the innate immune system. A dysregulated immune …

Risk factors associated with the clinical outcomes of COVID-19 and its variants in the context of cytokine storm and therapeutics/vaccine development challenges

J Hanna, P Tipparaju, T Mulherkar, E Lin, V Mischley… - Vaccines, 2021 - mdpi.com
The recent appearance of SARS-CoV-2 is responsible for the ongoing coronavirus disease
2019 (COVID-19) pandemic and has brought to light the importance of understanding this …

Differential cytokine signatures of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza infection highlight key differences in pathobiology

AH Karaba, W Zhou, LL Hsieh… - Clinical Infectious …, 2022 - academic.oup.com
Background Several inflammatory cytokines are upregulated in severe coronavirus disease
2019 (COVID-19). We compared cytokines in COVID-19 versus influenza to define …

Cytokine storm may not be the chief culprit for the deterioration of COVID-19

Y Gao, C Wang, K Kang, Y Peng, Y Luo, H Liu… - Viral …, 2021 - liebertpub.com
COVID-19 is spreading and ravaging all over the world, and the number of deaths is
increasing day by day without downward trend. However, there is limited knowledge of …

The deciphering of the immune cells and marker signature in COVID‐19 pathogenesis: An update

SA Jasim, RS Mahdi, DO Bokov… - Journal of Medical …, 2022 - Wiley Online Library
The precise interaction between the immune system and severe acute respiratory syndrome
coronavirus 2 (SARS‑CoV‑2) is critical in deciphering the pathogenesis of coronavirus …

Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …