Uncovering the mechanisms of dandelion against triple-negative breast cancer using a combined network pharmacology, molecular pharmacology and metabolomics …

J Qu, F Ke, Z Liu, X Yang, X Li, H Xu, Q Li, K Bi - Phytomedicine, 2022 - Elsevier
Background Taraxacum mongolicum, also called dandelion, has been used for thousands of
years as a remedy for mammary abscess, mammary gland hyperplasia, and various other …

[HTML][HTML] Dandelion extract inhibits triple-negative breast cancer cell proliferation by interfering with glycerophospholipids and unsaturated fatty acids metabolism

S Wang, H Hao, Y Jiao, J Fu, Z Guo, Y Guo… - Frontiers in …, 2022 - frontiersin.org
Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype with
limited treatment options and a poor prognosis. TNBC exists widely reprogrammed lipid …

Taraxacum mongolicum extract inhibited malignant phenotype of triple-negative breast cancer cells in tumor-associated macrophages microenvironment through …

XX Deng, YN Jiao, HF Hao, D Xue, CC Bai… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Triple-negative breast cancer (TNBC) is the most
aggressive and the worst prognosis breast cancer with limited treatment options. Taraxacum …

Taraxacum mongolicum extract induced endoplasmic reticulum stress associated-apoptosis in triple-negative breast cancer cells

XH Li, XR He, YY Zhou, HY Zhao, WX Zheng… - Journal of …, 2017 - Elsevier
Background Triple-negative breast cancer (TNBC) is an aggressive and deadly breast
cancer subtype with limited treatment options. It is necessary to seek complementary …

Exploring the pharmacological mechanism of Danzhi Xiaoyao powder on ER‐positive breast cancer by a network pharmacology approach

K Yang, L Zeng, J Ge - Evidence‐Based Complementary and …, 2018 - Wiley Online Library
Background. Breast cancer is the most common malignancy among women worldwide, but
the long‐term endocrine therapy is frequently associated with adverse side effects. Danzhi …

[HTML][HTML] Network pharmacology–based identification of key mechanisms of xihuang pill in the treatment of triple-negative breast cancer stem cells

YZ Zhang, JY Yang, RX Wu, C Fang, H Lu… - Frontiers in …, 2021 - frontiersin.org
Xihuang pill, an approved Chinese medicine formula (state medical permit number.
Z11020073), is a commonly used adjuvant drug for cancer patients in China. Xihuang pill …

β, β-Dimethylacrylshikonin potentiates paclitaxel activity, suppresses immune evasion and triple negative breast cancer progression via STAT3Y705 phosphorylation …

Z Wu, H Wu, Z Wang, H Li, H Gu, E Xia, C Yan, Y Dai… - Phytomedicine, 2023 - Elsevier
Backgound Triple negative breast cancer (TNBC) is an extremely aggressive and rapidly
progressing cancer, wherein existing therapies provide little benefit to patients. β, β …

[HTML][HTML] The inhibitory effect and mechanism of Resina Draconis on the proliferation of MCF-7 breast cancer cells: a network pharmacology-based analysis

Y Lv, Y Mou, J Su, S Liu, X Ding, Y Yuan, G Li, G Li - Scientific Reports, 2023 - nature.com
Resina Draconis (RD) is known as the" holy medicine for promoting blood circulation" and
possesses antitumor properties against various types of cancer, including breast cancer …

[HTML][HTML] A mechanism of action study on Danggui Sini decoction to discover its therapeutic effect on gastric cancer

B Pan, Y Wang, C Wu, J Jia, C Huang… - Frontiers in …, 2021 - frontiersin.org
Danggui Sini Decoction (DSD), a classic Chinese herb medicine (CHM) formula, has been
used to treat various diseases in China for centuries. However, it remains challenging to …

[HTML][HTML] Anti-colon Cancer Effects of Dendrobium officinale Kimura & Migo Revealed by Network Pharmacology Integrated With Molecular Docking and Metabolomics …

S Tao, J Li, H Wang, S Ding, W Han, R He… - Frontiers in …, 2022 - frontiersin.org
Objective The present study aimed to investigate the potential mechanism of Dendrobium
officinale (D. officinale) on colorectal cancer and the relevant targets in the pathway using a …