[HTML][HTML] Anti-tumor potential and mode of action of karanjin against breast cancer; an in-silico approach

PSR Dwivedi, CS Shastry - Arabian Journal of Chemistry, 2023 - Elsevier
Karanjin is a furanoflavanoid first isolated from Pongamia pinnata and has been reported to
possess a cytotoxic effect on various lung, breast, leukemia, and hepatoma cancers …

Exploring mechanism of key Chinese herbal medicine on breast cancer by data mining and network pharmacology methods

L Yang, Z Wu, Z Yang, S Li, C Ouyang - Chinese journal of integrative …, 2021 - Springer
Objective To screen the key Chinese Herbal Medicines (KCHMs) against breast cancer by
data mining, and analyze the potential mechanism of KCHMs using network pharmacology …

Network Pharmacology and Bioinformatics Approach Reveals the Multi-Target Pharmacological Mechanism of Fumaria indica in the Treatment of Liver Cancer

S Batool, MR Javed, S Aslam, F Noor, HMF Javed… - Pharmaceuticals, 2022 - mdpi.com
Liver cancer (LC), a frequently occurring cancer, has become the fourth leading cause of
cancer mortality. The small number of reported data and diverse spectra of …

Molecular targets of Chinese herbs: a clinical study of metastatic colorectal cancer based on network pharmacology

H Zhu, J Hao, Y Niu, D Liu, D Chen, X Wu - Scientific reports, 2018 - nature.com
Increasing evidence has shown that Chinese herbal medicine (CHM) has promising
therapeutic effects in colorectal cancer (CRC); however, the active ingredients and potential …

Network pharmacology-oriented identification of key proteins and signaling pathways targeted by Xihuang pill in the treatment of breast cancer

J Wu, D Luo, S Li - Breast Cancer: Targets and Therapy, 2020 - Taylor & Francis
Purpose The compound traditional Chinese medicine Xihuang pill (XHP) has been adopted
to treat breast cancer (BC) for centuries, but its specific mechanism of action is unclear …

6‐Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF‐7 cells by accumulating ROS to suppress the PI3K/AKT/mTOR signaling …

L Zhang, X Zhang, D Che, L Zeng… - Phytotherapy …, 2023 - Wiley Online Library
Methoxydihydrosanguinarine (6‐MDS) is a natural benzophenanthridine alkaloid extracted
from Hylomecon japonica (Thunb.) Prantl. It is the first time to explore the effect and …

A Combined Phytochemistry and Network Pharmacology Approach to Reveal Potential Anti-NSCLC Effective Substances and Mechanisms in Marsdenia tenacissima …

P Liu, DW Xu, RT Li, SH Wang, YL Hu, SY Shi… - Frontiers in …, 2021 - frontiersin.org
Marsdeniae tenacissimae Caulis is a traditional Chinese medicine, named Tongguanteng
(TGT), that is often used for the adjuvant treatment of cancer. In our previous study, we …

Network pharmacology-based study on apigenin present in the methanolic fraction of leaves extract of Cestrum nocturnum L. to uncover mechanism of action on …

P Kumar, AK Singh, P Verma, KN Tiwari, SK Mishra - Medical Oncology, 2022 - Springer
Hepatocellular carcinoma (HCC) is the sixth most common type of cancer in the world. It is
the third leading cause of cancer-related mortality. In more than 80% of people liver cancer …

Tetrandrine inhibits cancer stem cell characteristics and epithelial to mesenchymal transition in triple-negative breast cancer via SOD1/ROS signaling pathway

T Liu, K Li, Z Zhang, J Peng, J Yang… - The American Journal …, 2023 - World Scientific
Targeting the stemness of triple-negative breast cancer (TNBC) is a potential therapeutic
approach for treating TNBC. Tetrandrine, a natural plant alkaloid, has several anticancer …

Daidzein exerts anticancer activity towards SKOV3 human ovarian cancer cells by inducing apoptosis and cell cycle arrest, and inhibiting the Raf/MEK/ERK cascade …

F Hua, CH Li, XG Chen, XP Liu - … journal of molecular …, 2018 - spandidos-publications.com
Ovarian cancer is the main cause of gynecological cancer‑associated mortality around the
world. Despite initial responses to chemotherapy, frequent relapse occurs. Daidzein is an …