[HTML][HTML] Network analysis and mechanisms of action of Chinese herb-related natural compounds in lung cancer cells

YJ Lin, WM Liang, CJ Chen, H Tsang, JS Chiou, X Liu… - Phytomedicine, 2019 - Elsevier
Abstract Background Chinese herbal medicines (CHMs) are a resource of natural
compounds (ingredients) and their potential chemical derivatives with anticancer properties …

Jatrorrhizine inhibits mammary carcinoma cells by targeting TNIK mediated Wnt/β-catenin signalling and epithelial-mesenchymal transition (EMT)

Y Sun, X Gao, P Wu, M Wink, J Li, L Dian, Z Liang - Phytomedicine, 2019 - Elsevier
Abstract Background Traf2 and Nck interacting serine protein kinase (TNIK) is a tumour
target protein which its high expression is closely related to the occurrence and …

Scutellaria barbata and Hedyotis diffusa herb pair for breast cancer treatment: Potential mechanism based on network pharmacology

TT Ma, GL Zhang, CF Dai, BR Zhang, KX Cao… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance The Scutellaria barbata and Hedyotis diffusa (SH)
herb pair is extensively used in Traditional Chinese Medicine for efficacy enhancement in …

Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α-glycyrrhetinic acid against non-small cell lung cancer

R Irshad, N Raj, GA Gabr, N Manzoor… - Frontiers in …, 2022 - frontiersin.org
Non-small cell lung cancer (NSCLC) is one of the most malignant types of cancer with
soaring incidence rates worldwide, attributed to its heterogeneity and complex etiology …

Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells

X Shi, W Zhang, X Bao, X Liu, M Yang… - Frontiers in …, 2023 - frontiersin.org
Background The most aggressive subtype of breast cancer, triple-negative breast cancer
(TNBC), has a worse prognosis and a higher probability of relapse since there is a narrow …

Exploring the pharmacological mechanism of Yanghe Decoction on HER2-positive breast cancer by a network pharmacology approach

L Zeng, K Yang - Journal of Ethnopharmacology, 2017 - Elsevier
Abstract Ethnopharmacological relevance Certain Chinese medicine formulae from
traditional Chinese Medicine (TCM) are effective for treating and preventing diseases in …

Effects of Luteolin on human breast cancer using gene expression Array: Inferring novel genes

SH Wang, CH Wu, CC Tsai, TY Chen, KJ Tsai… - Current Issues in …, 2022 - mdpi.com
Taraxacum officinale (dandelion) is often used in traditional Chinese medicine for the
treatment of cancer; however, the downstream regulatory genes and signaling pathways …

Ingenane-type diterpenoids inhibit non-small cell lung cancer cells by regulating SRC/PI3K/Akt pathway

XY Wang, YJ Wang, ZL Hou, BW Guo… - Natural Product …, 2023 - Taylor & Francis
Ingenane-type diterpenoids (ITDs) are distinct components of plants belonging to the genus
Euphorbia. These compounds have significant cytotoxic effects on non-small cell lung …

The mechanism of flavonoids from Cyclocarya paliurus on inhibiting liver cancer based on in vitro experiments and network pharmacology

J Mo, Y Tong, J Ma, K Wang, Y Feng, L Wang… - Frontiers in …, 2023 - frontiersin.org
Introduction: Cyclocarya paliurus (Batal.) Iljinsk., a subtropical tree belonging to the family
Juglandaceae, is rich in polysaccharides, flavonoids, and terpenoids. It has important …

A network pharmacology approach to uncover the potential mechanism of Yinchensini decoction

G Chen, C Huang, Y Liu, T Chen… - Evidence‐Based …, 2018 - Wiley Online Library
Objective. To predict and explore the potential mechanism of Yinchensini decoction
(YCSND) based on systemic pharmacology. Method. TCMSP database was searched for …