The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2

S Muralidar, SV Ambi, S Sekaran, UM Krishnan - Biochimie, 2020 - Elsevier
An acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
The coronavirus disease 2019 pandemic caused by severe acute respiratory syndrome
coronavirus 2 presents with a spectrum of clinical manifestations from asymptomatic or mild …

Immunologic aspects of characteristics, diagnosis, and treatment of coronavirus disease 2019 (COVID-19)

FY Chang, HC Chen, PJ Chen, MS Ho… - Journal of biomedical …, 2020 - Springer
Abstract On March 11, 2020, the World Health Organization declared the worldwide spread
of the infectious disease COVID-19, caused by a new strain of coronavirus, SARS-CoV-2, as …

The development of COVID-19 treatment

Y Yuan, B Jiao, L Qu, D Yang, R Liu - Frontiers in immunology, 2023 - frontiersin.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused
a pandemic named coronavirus disease 2019 (COVID-19) that has become the greatest …

Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent

A Mazzoni, L Salvati, L Maggi… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Coronavirus disease 19 (COVID-19) is an emerging infectious disease
caused by SARS-CoV-2. Antiviral immune response is crucial to achieve pathogen …

Overview of immune response during SARS-CoV-2 infection: lessons from the past

VK Shah, P Firmal, A Alam, D Ganguly… - Frontiers in …, 2020 - frontiersin.org
After the 1918 flu pandemic, the world is again facing a similar situation. However, the
advancement in medical science has made it possible to identify that the novel infectious …

Inflammation and antiviral immune response associated with severe progression of COVID-19

Q Zhang, Y Meng, K Wang, X Zhang, W Chen… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease-2019 (COVID-19) is a novel respiratory disease induced by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It remains poorly understood how …

[HTML][HTML] The COVID-19 cytokine storm; what we know so far

D Ragab, H Salah Eldin, M Taeimah… - Frontiers in …, 2020 - frontiersin.org
COVID-19 is a rapidly spreading global threat that has been declared as a pandemic by the
WHO. COVID-19 is transmitted via droplets or direct contact and infects the respiratory tract …

Humoral immune responses in COVID-19 patients: a window on the state of the art

G Siracusano, C Pastori, L Lopalco - Frontiers in immunology, 2020 - frontiersin.org
The novel SARS-CoV-2 is a recently emerging virus causing a human pandemic. A great
variety of symptoms associated with COVID-19 disease, ranging from mild to severe …

Host immune response and immunobiology of human SARS-CoV-2 infection

S Kumar, R Nyodu, VK Maurya, SK Saxena - Coronavirus Disease 2019 …, 2020 - Springer
One of the most serious viral outbreaks of the decade, infecting humans, originated from the
city of Wuhan, China, by the end of December 2019, has left the world shaken up. It is the …