SARS-CoV-2: immune response elicited by infection and development of vaccines and treatments

G Canedo-Marroquin, F Saavedra… - Frontiers in …, 2020 - frontiersin.org
The World Health Organization (WHO) announced in March a pandemic caused by Severe
Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This new infectious disease was …

Immunotherapy of COVID-19: inside and beyond IL-6 signalling

G Zizzo, A Tamburello, L Castelnovo, A Laria… - Frontiers in …, 2022 - frontiersin.org
Acting on the cytokine cascade is key to preventing disease progression and death in
hospitalised patients with COVID-19. Among anti-cytokine therapies, interleukin (IL)-6 …

Interleukin-1 in COVID-19 Infection: Immunopathogenesis and Possible Therapeutic Perspective

A Mardi, S Meidaninikjeh, S Nikfarjam… - Viral …, 2021 - liebertpub.com
The newfound coronavirus disease 2019 (COVID-19), initiated by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is an international public health concern …

Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages

M Merad, JC Martin - Nature reviews immunology, 2020 - nature.com
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than
200,000 deaths worldwide. Several studies have now established that the …

Heightened innate immune responses in the respiratory tract of COVID-19 patients

Z Zhou, L Ren, L Zhang, J Zhong, Y Xiao, Z Jia, L Guo… - Cell host & …, 2020 - cell.com
The outbreaks of 2019 novel coronavirus disease (COVID-19) caused by SARS-CoV-2
infection have posed a severe threat to global public health. It is unclear how the human …

The dynamic changes in cytokine responses in COVID-19: a snapshot of the current state of knowledge

M Buszko, JH Park, D Verthelyi, R Sen, HA Young… - Nature …, 2020 - nature.com
“The role of cytokines in COVID-19” online symposium was presented on 18 June 2020 by
the NIH/FDA Immunology and Cytokine Interest Groups and was purposed to discuss our …

The immunology and immunopathology of COVID-19

M Merad, CA Blish, F Sallusto, A Iwasaki - Science, 2022 - science.org
Considerable research effort has been made worldwide to decipher the immune response
triggered upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections …

COVID-19: infection or autoimmunity

T Icenogle - Frontiers in immunology, 2020 - frontiersin.org
The clinical and laboratory features of COVID-19 are reviewed with attention to the
immunologic manifestations of the disease. Recent COVID-19 publications describe a …

Back to basics in COVID‐19: antigens and antibodies—completing the puzzle

M Neagu, D Calina, AO Docea… - Journal of Cellular …, 2021 - Wiley Online Library
The outbreak of the coronavirus disease 2019 (COVID‐19) has gathered 1 year of
scientific/clinical information. This informational asset should be thoroughly and wisely used …

SARS-CoV-2 triggering autoimmune diseases

L Mobasheri, MH Nasirpour, E Masoumi… - Cytokine, 2022 - Elsevier
Autoimmunity, hyperstimulation of the immune system, can be caused by a variety of
reasons. Viruses are thought to be important environmental elements that contribute to the …