Age-related neural dedifferentiation—a decline in the distinctiveness of neural
representations in the aging brain—has been associated with age-related declines in …

Neural activation patterns in the ventral visual cortex in response to different categories of
visual stimuli (eg, faces vs. houses) are less selective, or distinctive, in older adults than in …

Several studies have attributed certain visual perceptual alterations in older adults to a likely
decrease in GABA (Gamma Aminobutyric Acid) concentration in visual cortex, an …

Background Aging is often associated with behavioral impairments, but some people age
more gracefully than others. Why? One factor that may play a role is individual differences in …

Electrophysiological studies indicate that a decline of GABAergic inhibition in the visual
cortex may underlie age-related degradation of visual function [AG Leventhal, Y. Wang, M …

According to the neural dedifferentiation hypothesis, age-related reductions in the
distinctiveness of neural representations contribute to sensory, cognitive, and motor declines …

Dedifferentiation, or decreased processing specificity, has been suggested to represent a
ubiquitous characteristic of cognitive aging. In this study, we examined both age-related …

Current theories of cognitive aging argue that neural representations become less distinctive
in old age, a phenomenon known as dedifferentiation. The present study used multi-voxel …

Numerous studies have reported age-dependent degradation of neuronal function in the
visual cortex and have attributed this functional decline to weakened intracortical inhibition …

The aging brain is characterized by neural dedifferentiation, an apparent decrease in the
functional selectivity of category-selective cortical regions. Age-related reductions in neural …