Abstract Background In December 2019, a novel human-infecting coronavirus, SARS-CoV-
2, had emerged. The WHO has classified the epidemic as a “public health emergency of …

Aging and senescence are complex processes associated with increased frailty (Calimport,
Bentley, & Stewart, 2019). Overall, many pathogens are more aggressive and prevalent in …

The unprecedented COVID-19 pandemic is rapidly and unpredictably evolving and the
majority of deaths are occurring in older people. A partial description of the magnitude of the …

The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people
with cardiovascular disease have been proven. New findings shed light on the role of aging …

Main cause of severe illness and death in COVID-19 patients appears to be an excessive
but ineffectual inflammatory immune response that may cause severe acute respiratory …

As people get older, age-related alterations occur that lead to increased susceptibility to
disease. In the current COVID-19 pandemic, older people are particularly susceptible to a …

Old individuals are more susceptible to various infections due to immunological changes
that occur during the aging process. These changes named collectively as …

Abstract Importance: Among COVID-19 cases, especially the (frail) elderly show a high
number of severe infections, hospital admissions, complications, and death. The highest …

Objectives We present evidence for a possible role of Vitamin D (VitD) deficiency in
unregulated cytokine production and inflammation leading to complications in COVID-19 …

The last few months of 2019 witnessed the emergence, rise and rapid spread of a novel
coronavirus known as severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …