Grey matter connectome abnormalities and age-related effects in antipsychotic-naive schizophrenia

B Yang, W Zhang, R Lencer, B Tao, B Tang, J Yang… - …, 2021 - thelancet.com
Background Convergent evidence is increasing to indicate progressive brain abnormalities
in schizophrenia. Knowing the brain network features over the illness course in …

Disrupted structural covariance network in first episode schizophrenia patients: evidence from a large sample MRI-based morphometric study

X Zhang, W Liu, F Guo, C Li, X Wang, H Wang… - Schizophrenia …, 2020 - Elsevier
Background Recent progress in neuroscience research has provided evidence that
schizophrenia is a disease that involves dysconnectivity of brain networks. Widespread gray …

White matter connectivity disruptions in early and chronic schizophrenia

MA Di Biase, VL Cropley, BT Baune, J Olver… - Psychological …, 2017 - cambridge.org
BackgroundWhite matter disruptions in schizophrenia have been widely reported, but it
remains unclear whether these abnormalities differ between illness stages. We mapped the …

Connectome-based patterns of first-episode medication-naive patients with schizophrenia

LB Cui, Y Wei, YB Xi, A Griffa, SC De Lange… - Schizophrenia …, 2019 - academic.oup.com
Emerging evidence indicates that a disruption in brain network organization may play an
important role in the pathophysiology of schizophrenia. The neuroimaging fingerprint …

Brain network functional connectivity changes in long illness duration chronic schizophrenia

YX Bai, JX Luo, D Peng, JJ Sun, YF Gao… - Frontiers in …, 2024 - frontiersin.org
Introduction Chronic schizophrenia has a course of 5 years or more and has a widespread
abnormalities in brain functional connectivity. This study aimed to find characteristic …

Characteristics of disrupted topological organization in white matter functional connectome in schizophrenia

Y Jiang, D Yao, J Zhou, Y Tan, H Huang… - Psychological …, 2022 - cambridge.org
BackgroundNeuroimaging characteristics have demonstrated disrupted functional
organization in schizophrenia (SZ), involving large-scale networks within grey matter (GM) …

Disrupted subcortical functional connectome gradient in drug-naïve first-episode schizophrenia and the normalization effects after antipsychotic treatment

C Yang, W Zhang, J Liu, L Yao, JR Bishop… - …, 2023 - nature.com
Antipsychotics are thought to improve schizophrenia symptoms through the antagonism of
dopamine D2 receptors, which are abundant mainly in subcortical regions. By introducing …

Alterations of intrinsic connectivity networks in antipsychotic-naïve first-episode schizophrenia

S Anhøj, M Ødegaard Nielsen, MH Jensen… - Schizophrenia …, 2018 - academic.oup.com
Background The investigation of large-scale intrinsic connectivity networks in antipsychotic-
naïve first-episode schizophrenia increases our understanding of system-level cerebral …

[HTML][HTML] Disruption of structure–function coupling in the schizophrenia connectome

L Cocchi, IH Harding, A Lord, C Pantelis, M Yucel… - NeuroImage: Clinical, 2014 - Elsevier
Neuroimaging studies have demonstrated that the phenomenology of schizophrenia maps
onto diffuse alterations in large-scale functional and structural brain networks. However, the …

Heterogeneous Brain Abnormalities in Schizophrenia Converge on a Common Network Associated With Symptom Remission

Y Wang, Y Yang, W Xu, X Yao, X Xie… - Schizophrenia …, 2024 - academic.oup.com
Abstract Background and Hypothesis There is a huge heterogeneity of magnetic resonance
imaging findings in schizophrenia studies. Here, we hypothesized that brain regions …