Bacteriophage (phage) therapy is an alternative to traditional antibiotic treatments that is
particularly important for multidrug-resistant pathogens, such as Pseudomonas aeruginosa …

Clinical isolates of Pseudomonas aeruginosa that hyperproduce a dark-brown pigment are
quite often found in the lungs of chronically infected patients, suggesting that they may have …

Viruses that infect bacteria (ie, phages) are abundant and widespread in the human body,
and new anti-infective approaches such as phage therapy are essential for the future of …

Pseudomonas aeruginosa is responsible for long-term infections and is particularly resistant
to treatments when hiding inside the extracellular matrix or biofilms. Phage therapy might …

The increasing ineffectiveness of traditional antibiotics and the rise of multidrug resistant
(MDR) bacteria have necessitated the revival of bacteriophage (phage) therapy. However …

Prokaryotes encode multiple distinct anti-phage defense systems in their genomes.
However, the impact of carrying a multitude of defense systems on phage resistance …

Bacteria develop a broad range of phage resistance mechanisms, such as prevention of
phage adsorption and CRISPR/Cas system, to survive phage predation. In this study …

In this study, we have investigated innate immune activation capacity and metabolic features
of a population of P. aeruginosa PAO1 phage-resistant mutants with diverse genetic …

The emergence and spread of antibiotic resistance pose serious environmental and health
challenges. Attention has been drawn to phage therapy as an alternative approach to …

Pseudomonas aeruginosa, which causes chronic infections, has demonstrated rapid
acquisition of antimicrobial resistance (AMR). Therefore, bacteriophages have received …