Considerations for target oxygen saturation in COVID-19 patients: are we under-shooting?

N Shenoy, R Luchtel, P Gulani - BMC medicine, 2020 - Springer
Background The current target oxygen saturation range for patients with COVID-19
recommended by the National Institutes of Health is 92–96%. Main body This article critically …

Lower vs higher oxygenation target and days alive without life support in COVID-19: the HOT-COVID randomized clinical trial

FM Nielsen, TL Klitgaard, M Siegemund, JH Laake… - JAMA, 2024 - jamanetwork.com
Importance Supplemental oxygen is ubiquitously used in patients with COVID-19 and
severe hypoxemia, but a lower dose may be beneficial. Objective To assess the effects of …

Clinical outcomes associated with overestimation of oxygen saturation by pulse oximetry in patients hospitalized with COVID-19

A Fawzy, TD Wu, K Wang, KE Sands… - JAMA Network …, 2023 - jamanetwork.com
Importance Many pulse oximeters have been shown to overestimate oxygen saturation in
persons of color, and this phenomenon has potential clinical implications. The relationship …

Basing respiratory management of COVID-19 on physiological principles

MJ Tobin - American journal of respiratory and critical care …, 2020 - atsjournals.org
The dominant respiratory feature of coronavirus disease (COVID-19) is arterial hypoxemia
greatly exceeding abnormalities in pulmonary mechanics (decreased compliance)(1–3) …

Association between hypoxemia and mortality in patients with COVID-19

J Xie, N Covassin, Z Fan, P Singh, W Gao, G Li… - Mayo Clinic …, 2020 - Elsevier
Objective To identify markers associated with in-hospital death in patients with coronavirus
disease 2019 (COVID-19)–associated pneumonia. Patients and Methods A retrospective …

Oxygen and mortality in COVID-19 pneumonia: a comparative analysis of supplemental oxygen policies and health outcomes across 26 countries

F Mansab, H Donnelly, A Kussner, J Neil… - Frontiers in Public …, 2021 - frontiersin.org
Introduction: Hypoxia is the main cause of morbidity and mortality in COVID-19. During the
COVID-19 pandemic, some countries have reduced access to supplemental oxygen …

Oxygen saturation as a predictor of mortality in hospitalized adult patients with COVID-19 in a public hospital in Lima, Peru

F Mejía, C Medina, E Cornejo, E Morello, S Vásquez… - PloS one, 2020 - journals.plos.org
Introduction Peru is among the top ten countries with the highest number of coronavirus
disease 2019 (COVID-19) cases worldwide. The aim of the study was to describe the clinical …

Clinical course of COVID-19 patients needing supplemental oxygen outside the intensive care unit

A Daher, P Balfanz, M Aetou, B Hartmann… - Scientific Reports, 2021 - nature.com
Patients suffering from CVOID-19 mostly experience a benign course of the disease.
Approximately 14% of SARS-CoV2 infected patients are admitted to a hospital. Cohorts …

Benefits and risks of noninvasive oxygenation strategy in COVID-19: a multicenter, prospective cohort study (COVID-ICU) in 137 hospitals

Critical Care, 2021 - Springer
Rational To evaluate the respective impact of standard oxygen, high-flow nasal cannula
(HFNC) and noninvasive ventilation (NIV) on oxygenation failure rate and mortality in COVID …

[HTML][HTML] The association between mortality and the oxygen saturation and fraction of inhaled oxygen in patients requiring oxygen therapy due to COVID-19 …

KJ Choi, HL Hong, EJ Kim - Tuberculosis and Respiratory …, 2021 - ncbi.nlm.nih.gov
Background The coronavirus disease (COVID-19) can manifest in a range of symptoms,
including both asymptomatic systems which appear nearly non-existent to the patient, all the …