Myelination is key to effective message passing in the central nervous system and is likely
linked to the pathogenesis of schizophrenia (SZ). Emerging evidence indicates that a large …

Aberrations in intracortical myelination are increasingly being considered as a cardinal
feature in the pathophysiology of schizophrenia. We investigated the network-level …

Background Postmortem and imaging studies provide converging evidence that the frontal
lobe myelination trajectory is dysregulated in schizophrenia (SZ) and suggest that early in …

CONTEXT: Imaging and post-mortem studies provide converging evidence that patients with
schizophrenia have a dysregulated developmental trajectory of frontal lobe myelination. The …

Myelin abnormalities have been reported in schizophrenia spectrum disorders (SSD) in
white matter. However, in vivo examinations of cortical myeloarchitecture in SSD, especially …

Background Previous studies imply that interhemispheric disconnectivity plays a more
important role on information processing in schizophrenia. However, the role of the aberrant …

Background In schizophrenia (SZ), disturbances in integration of activity among brain
regions seem to be as important as abnormal activity of any single region. Brain regions are …

Psychotic illness has consistently been associated with deficits in cognitive function and
reduced white matter integrity in the brain. However, the link between white matter …

Little is known about the structural brain changes that occur over the first few years of
schizophrenia, or how these changes differ from those associated with healthy brain …

Background Grey matter (GM) reduction is a consistent observation in established late
stages of schizophrenia, but patients in the untreated early stages of illness display an …