Within the past several decades, the emergence and spread of infectious diseases with
pandemic potential have endangered human lives. Coronavirus disease 2019 (COVID-19) …

Telomere shortening, a marker of cellular aging, has been linked to hospitalization and the
severity of COVID-19. In this systematic review and meta-analysis, the mean difference in …

Telomeres are non-coding DNA sequences that protect chromosome ends and shorten with
age. Short telomere length (TL) is associated with chronic diseases and …

The incidence of severe manifestations of COVID-19 increases with age with older patients
showing the highest mortality, suggesting that molecular pathways underlying aging …

The global impact of the SARS-CoV-2 pandemic has been unprecedented, posing a
significant public health challenge. Chronological age has been identified as a key …

Background Inter-individual variations in the clinical manifestations of SARS-CoV-2 infection
are among the challenging features of COVID-19. The known role of telomeres in cell …

In December of 2019, an outbreak of pneumonia of unknown cause was reported in Wuhan,
Hubei Province, China. By January 2020, a novel coronavirus—that was named severe …

The SARS-CoV-2 infection determines the COVID-19 syndrome characterized, in the worst
cases, by severe respiratory distress, pulmonary and cardiac fibrosis, inflammatory cytokine …

Observational data from China, the United States, France, and Italy suggest that
chronological age is an adverse COVID-19 outcome risk factor, with older patients having a …

Age is a major risk factor for severe outcome of the 2019 coronavirus disease (COVID-19). In
this study, we followed the hypothesis that particularly patients with accelerated epigenetic …