Glyoxal in foods: Formation, metabolism, health hazards, and its control strategies

M Zhang, C Huang, J Ou, F Liu, S Ou… - Journal of Agricultural …, 2024 - ACS Publications
Glyoxal is a highly reactive aldehyde widely present in common diet and environment and
inevitably generated through various metabolic pathways in vivo. Glyoxal is easily produced …

Trapping of glyoxal by propyl, octyl and dodecyl gallates and their mono-glyoxal adducts

Y Hou, Z Xie, H Cui, Y Lu, T Zheng, S Sang, L Lv - Food chemistry, 2018 - Elsevier
Glyoxal (GO) is one of the major toxic intermediates generated during lipid oxidation and
degradation. We investigated the inhibitory activities and mechanisms of propyl, octyl, and …

Flavour chemistry of methylglyoxal and glyoxal

Y Wang, CT Ho - Chemical Society Reviews, 2012 - pubs.rsc.org
Methylglyoxal (MGO) and glyoxal (GO), known as reactive carbonyl species, can be
generated endogenously and exogenously (human body and food system). They are …

Toxicity of glyoxals–role of oxidative stress, metabolic detoxification and thiamine deficiency

N Shangari, WR Bruce, R Poon… - Biochemical Society …, 2003 - portlandpress.com
Glyoxals are reactive α-oxoaldehydes that are formed endogenously from sugars, the levels
of which are increased in various pathological conditions associated with hyperglycaemia …

Benefits, deleterious effects and mitigation of methylglyoxal in foods: A critical review

J Zheng, H Guo, J Ou, P Liu, C Huang, M Wang… - Trends in Food Science …, 2021 - Elsevier
Background Methylglyoxal, a reactive carbonyl compound widely present in thermally
processed foods, is produced from sugar degradation and lipid oxidation. Methylglyoxal can …

Analysis, distribution, and dietary exposure of glyoxal and methylglyoxal in cookies and their relationship with other heat-induced contaminants

G Arribas-Lorenzo, FJ Morales - Journal of agricultural and food …, 2010 - ACS Publications
Thermal processing of food leads to the formation of dicarbonyls such as glyoxal (GO) and
methylglyoxal (MGO), which are potentially harmful because they are precursors of …

The cytotoxic mechanism of glyoxal involves oxidative stress

N Shangari, PJ O'Brien - Biochemical pharmacology, 2004 - Elsevier
Glyoxal is a reactive α-oxoaldehyde that is a physiological metabolite formed by lipid
peroxidation, ascorbate autoxidation, oxidative degradation of glucose and degradation of …

Scavenging Glyoxal and Methylglyoxal by Synephrine Alone or in Combination with Neohesperidin at High Temperatures

Y Liang, R Du, X Zhao, Y Xu, Q Xiang… - Journal of Agricultural …, 2024 - ACS Publications
α-Dicarbonyl compounds, such as glyoxal (GO) and methylglyoxal (MGO), are a series of
chemical hazards that exist in vivo and in vitro, posing a threat to human health. We aimed to …

Glyoxal and methylglyoxal formation in chocolate and their bioaccessibility

E Ede-Cintesun, J Çatak, E Ateş, M Yaman - Food Research International, 2024 - Elsevier
The objective of this study was to assess the effects of simulated digestion on the formation
of α-dicarbonyl compounds (α-DCs) in chocolates. For that purpose, the concentrations of …

Bacterial responses to glyoxal and methylglyoxal: reactive electrophilic species

C Lee, C Park - International journal of molecular sciences, 2017 - mdpi.com
Glyoxal (GO) and methylglyoxal (MG), belonging to α-oxoaldehydes, are produced by
organisms from bacteria to humans by glucose oxidation, lipid peroxidation, and DNA …