Humoral immune mechanisms involved in protective and pathological immunity during COVID-19

G Widjaja, AT Jalil, HS Rahman, WK Abdelbasset… - Human Immunology, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing COVID-19 is
associated with excessive inflammation, as a main reason for severe condition and death …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

Targeting inflammatory cytokine storm to fight against COVID-19 associated severe complications

R Hirawat, MA Saifi, C Godugu - Life sciences, 2021 - Elsevier
Such testing and trying time probably never seen before in the human history. The novel
coronavirus disease abbreviated as COVID-19 is the ongoing health crisis which entered …

SARS-CoV-2 mediated lung inflammatory responses in host: targeting the cytokine storm for therapeutic interventions

P Asrani, MI Hassan - Molecular and Cellular Biochemistry, 2021 - Springer
The recent exposure of novel coronavirus strain, severe acute respiratory syndrome (SARS-
CoV-2) has spread to different countries at an alarming rate. Faster transmission rate and …

Inflammation in COVID-19 and the effects of non-pharmacological interventions during the pandemic: a review

VJ Clemente-Suárez, Á Bustamante-Sanchez… - International Journal of …, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the coronavirus
disease 2019 (COVID-19) pandemic that hit the health systems worldwide hard, causing a …

Severe COVID-19 shares a common neutrophil activation signature with other acute inflammatory states

LF Schimke, AHC Marques, GC Baiocchi… - Cells, 2022 - mdpi.com
Severe COVID-19 patients present a clinical and laboratory overlap with other
hyperinflammatory conditions such as hemophagocytic lymphohistiocytosis (HLH) …

Monocytes and macrophages in COVID-19: Friends and foes

S Meidaninikjeh, N Sabouni, HZ Marzouni, S Bengar… - Life sciences, 2021 - Elsevier
The COVID-19 is a novel infectious disease caused by SARS-CoV-2 and is known as a
pandemic emergency that has led to a high rate of mortality throughout the world. Evidence …

The role of dysregulated immune responses in COVID-19 pathogenesis

S Tahaghoghi-Hajghorbani, P Zafari, E Masoumi… - Virus research, 2020 - Elsevier
Abstract The coronavirus disease-2019 (COVID-19) which caused by severe acute
respiratory syndrome-related coronavirus (SARS-CoV-2), is a pandemic threat to global …

Immune response in COVID-19: addressing a pharmacological challenge by targeting pathways triggered by SARS-CoV-2

M Catanzaro, F Fagiani, M Racchi, E Corsini… - Signal transduction and …, 2020 - nature.com
To date, no vaccines or effective drugs have been approved to prevent or treat COVID-19
and the current standard care relies on supportive treatments. Therefore, based on the fast …

The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …