Abstract Formulation/pharmaceutical excipients play a major role in formulating drug
candidates, with the objectives of ease of administration, targeted delivery and complete …

Although the use of excipients is widespread, a thorough understanding of the drug
interaction potential of these compounds remains a frequent topic of current research. Not …

It is well-known that excipient is an integral part of most pharmaceutical formulations.
Although many conventional excipients possess some pros and cons, there is always a …

The development of excipient materials for use in drug formulations represents a growing
area of interest (and of invested time and cost) for pharmaceutical companies. Such …

Introduction Toxicology and pharmacology studies conducted in the early stages of drug
discovery often require formulation strategies involving the use of excipients with limited …

Abstract Formulation changes are common during drug development either due to clinical or
manufacturing considerations. These changes especially at later stages of drug …

Formulations play a key role in assessing the biological properties of a molecule during drug
discovery. Maximising exposure is the primary objective in early animal experimentation, so …

Pharmaceutical excipients have a vital role in drug formulations, a role that has tended to be
neglected as evidenced by the lack of mechanisms to assess excipient safety outside a new …

Excipients are ubiquitous in drug formulation, ensuring that active ingredient drugs are
properly released on dosing, retain their properties over time, and are palatable, among …

It is now recognized that a number of excipients previously considered to be “inert” have the
capacity to alter drug oral bioavailability through a range of in vivo effects. The various …