[HTML][HTML] IL-4/IL-13 remodeling pathway of COVID-19 lung injury

CB Vaz de Paula, MLV de Azevedo, S Nagashima… - Scientific Reports, 2020 - nature.com
… -4 may be secreted not only by the Th2 pathway but before it. In some … lung tissue expression
was higher in most of the COVID-19 patients since the beginning of the aggravated disease

[HTML][HTML] Pathological features of COVID-19-associated lung injury: a preliminary proteomics report based on clinical samples

L Leng, R Cao, J Ma, D Mou, Y Zhu, W Li, L Lv… - … and Targeted Therapy, 2020 - nature.com
… proteins in lungs of patients diagnosed with COVID-19. … expressed in COVID-19 and substrates
of KEGG pathways. Red … vascular remodeling, leading to the loss of respiratory function. …

[HTML][HTML] COVID-19: immunohistochemical analysis of TGF-β signaling pathways in pulmonary fibrosis

CB Vaz de Paula, S Nagashima, V Liberalesso… - International journal of …, 2021 - mdpi.com
… by repair with lung remodeling is observed in COVID-19. These findings can lead to … pathway
and the process of pulmonary remodeling in the severe forms of SARS-CoV-2 lung injury. …

[HTML][HTML] The immunopathological and histological landscape of COVID-19-mediated lung injury

G Zarrilli, V Angerilli, G Businello, M Sbaraglia… - International Journal of …, 2021 - mdpi.com
… ) within the cytokine storm could promote impaired tissue remodeling and lung fibrosis [67]. …
are intriguing, the precise pathways involved in COVID-19 are far from being completely …

Thromboinflammation in COVID-19 acute lung injury

WB Mitchell - Paediatric respiratory reviews, 2020 - Elsevier
… Macrophages are also recruited to fibrin thrombi and work to remodel the thrombus as part
… contact pathway activation. These pathways offer multiple targets for mitigation of COVID-19

Lung under attack by COVID-19-induced cytokine storm: pathogenic mechanisms and therapeutic implications

C Pelaia, C Tinello, A Vatrella… - … respiratory disease, 2020 - journals.sagepub.com
… as cytokine-dependent intracellular signalling pathways can be targeted by potential therapies
… favour tissue remodelling and lung fibrosis, 30 thus further compromising gas exchange. …

[HTML][HTML] SARS-CoV-2 and pathological matrix remodeling mediators

I Guizani, N Fourti, W Zidi, M Feki, M Allal-Elasmi - Inflammation Research, 2021 - Springer
… Since post COVID-19 pulmonary fibrosis is an emerging … , a remodeling takes place to respond
to lung injuries. However, … went through other possible pathways on viruses that belong to …

[HTML][HTML] Strategies to DAMPen COVID-19-mediated lung and systemic inflammation and vascular injury

C Bime, NG Casanova, J Nikolich-Zugich, KS Knox… - Translational …, 2021 - Elsevier
… immunity inflammatory pathways with unchecked lung and … as significant amplification of
these pathways by exposure to … The progressive lung damage is a combination of a profound …

[HTML][HTML] Hypoxia-inducible factor signaling in inflammatory lung injury and repair

CE Evans - Cells, 2022 - mdpi.com
… dysfunction and pathogenic remodeling [53,54,55,56]. … HIF signaling pathways regulate key
processes that drive … and repair of severe COVID-19 and ARDS lung injury. For example, the …

Histopathology features of the lung in COVID-19 patients

MA Montero-Fernandez, R Pardo-Garcia - Diagnostic Histopathology, 2021 - Elsevier
… local alteration of the coagulation pathway. Thrombi in DAD … COVID-19 showed predominantly
diffuse alveolar damage, … acute lung injury, depending in the length of the disease. …