[HTML][HTML] Evolution of antibody immunity to SARS-CoV-2

C Gaebler, Z Wang, JCC Lorenzi, F Muecksch, S Finkin… - Nature, 2021 - nature.com
… Eligible participants included adults, 18–76 years of age who were previously diagnosed
with SARS-CoV-2 by RT–PCR or through a combination of clinical symptoms consistent with …

[PDF][PDF] Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016

TN Starr, AJ Greaney, AS Dingens, JD Bloom - Cell Reports Medicine, 2021 - cell.com
… -2 spike receptor-binding domain (RBD) that escape binding by a leading monoclonal
antibody, LY-CoV555, and its cocktail combination with LY-CoV016. Individual mutations that …

[HTML][HTML] Antibody evasion properties of SARS-CoV-2 Omicron sublineages

S Iketani, L Liu, Y Guo, L Liu, JFW Chan, Y Huang… - Nature, 2022 - nature.com
… COV2-2130 (cilgavimab) and its combination with COV2-2196 (tixagevimab) retained activity
against BA.2, but this antibody combination is authorized only for preventive use. Only the …

The antibody response to SARS-CoV-2 infection

L Hueston, J Kok, A Guibone… - Open Forum …, 2020 - academic.oup.com
… or combinations of antibody classes are … antibody responses in SARS-CoV-2 infection,
but the waning IgG titers demonstrated in this study are in contrast to SARS-CoV and MERS-CoV

Considerable escape of SARS-CoV-2 Omicron to antibody neutralization

D Planas, N Saunders, P Maes, F Guivel-Benhassine… - Nature, 2022 - nature.com
… We also tested the antibodies in combination to mimic the therapeutic cocktails. Bamlanivimab
+ etesevimab (Lilly) or casirivimab + imdevimab (Ronapreve) were inactive against …

Antibody tests for identification of current and past infection with SARSCoV‐2

T Fox, J Geppert, J Dinnes, K Scandrett… - Cochrane database …, 2022 - cochranelibrary.com
… We present estimates of sensitivity and specificity for each antibody (or combination of
antibodies) using paired forest plots, and also summarised them in tables as appropriate. …

Convergent antibody responses to SARS-CoV-2 in convalescent individuals

DF Robbiani, C Gaebler, F Muecksch, JCC Lorenzi… - Nature, 2020 - nature.com
… To determine the nature of the antibodies elicited by SARS-CoV-2 infection, we used flow …
Finally, antibodies with recurrent combinations of IGHV and IGLV genes were among the …

Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B. 1.1. 529

T Zhou, L Wang, J Misasi, A Pegu, Y Zhang, DR Harris… - Science, 2022 - science.org
… Last, we assessed combinations of monoclonal antibodies and found several, … antibody
combinations that can be used for treatment and have demonstrated how these combinations

Resistance of SARS-CoV-2 variants to neutralization by monoclonal and serum-derived polyclonal antibodies

RE Chen, X Zhang, JB Case, ES Winkler, Y Liu… - Nature medicine, 2021 - nature.com
… introduced antibody and vaccine countermeasures. Here, using monoclonal antibodies (…
, we report the impact on antibody neutralization of a panel of authentic SARS-CoV-2 variants …

A combination of receptor-binding domain and N-terminal domain neutralizing antibodies limits the generation of SARS-CoV-2 spike neutralization-escape mutants

D Haslwanter, ME Dieterle, AZ Wec, CM O'brien… - Mbio, 2021 - Am Soc Microbiol
… These MAb therapeutics are solely targeting the receptor-binding domain of the SARS-CoV-2 …
We report that a combination of two neutralizing antibodies targeting the receptor-binding …