[HTML][HTML] Resilience of S309 and AZD7442 monoclonal antibody treatments against infection by SARS-CoV-2 Omicron lineage strains

JB Case, S Mackin, JM Errico, Z Chong… - Nature …, 2022 - nature.com
SARS-CoV-2 Omicron lineage strains (BA.1, BA.1.1, and BA.2) of two monoclonal antibody
… AZD7442 [AstraZeneca] combination), which correspond to ones used to treat or prevent …

[HTML][HTML] An engineered bispecific human monoclonal antibody against SARS-CoV-2

Z Li, S Li, G Zhang, W Peng, Z Chang, X Zhang… - Nature …, 2022 - nature.com
antibodies are a promising therapy. A noncompeting pair of human neutralizing antibodies
(B38 and H4) blocking SARS-CoV-… antibodies, antibody combinations and bsAb using SARS-…

[HTML][HTML] A narrative review of the clinical practicalities of bamlanivimab and etesevimab antibody therapies for SARS-CoV-2

R Nathan, I Shawa, I De La Torre, JM Pustizzi… - Infectious diseases and …, 2021 - Springer
… -19 prevention, neutralizing monoclonal antibodies (mAbs), … severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2)… As prevalence of SARS-CoV-2 variants can differ by country …

Monoclonal antibody therapies in the management of SARS-CoV-2 infection

E Miguez-Rey, D Choi, S Kim, S Yoon… - Expert Opinion on …, 2022 - Taylor & Francis
… A broad range of both novel and repurposed therapies have been evaluated as potential
treatments for SARS-CoV-2 infection, to be used in combination with supportive care measures…

[HTML][HTML] Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy

R Yamin, AT Jones, HH Hoffmann, A Schäfer, KS Kao… - Nature, 2021 - nature.com
… of anti-SARS-CoV-2 monoclonal antibodies with optimized … to confer full protection against
SARS-CoV-2 challenge and for … exceedingly high doses or in combination with remdesivir 5 . …

[HTML][HTML] Novel monoclonal antibodies and recombined antibodies against variant SARS-CoV-2

J Xie, C Ding, J He, Y Zhang, S Ni, X Zhang… - Frontiers in …, 2021 - frontiersin.org
SARS-CoV-2 epidemic have showed resistance to antibody … identified two novel SARS-CoV-2
neutralizing antibodies (nAbs) … A combination or cocktail therapy with multiple nAbs might …

Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11

J Fedry, DL Hurdiss, C Wang, W Li, G Obal, I Drulyte… - Science …, 2021 - science.org
SARS-CoV-2 spike, suggesting that it could be used effectively in combination with other
antibodies … Together, these results reveal a cross-protective epitope on the SARS-CoV-2 spike …

Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail

J Hansen, A Baum, KE Pascal, V Russo, S Giordano… - Science, 2020 - science.org
… anti-spike mAbs and combinations of mAbs against replicating VSV-SARS-CoV-2-S virus in
… anti-spike mAbs and combinations of mAbs against SARS-CoV-2-S virus in VeroE6 cells. …

Revealing the threat of emerging SARS-CoV-2 mutations to antibody therapies

J Chen, K Gao, R Wang, GW Wei - Journal of molecular biology, 2021 - Elsevier
… Lastly, we study C135 and C144, another antibody combination treatment currently on
phase 1 study. Due to fact that there is no 3D structure of C135 and C144 binding to RBD …

[HTML][HTML] Antibody evasion by SARS-CoV-2 Omicron subvariants BA. 2.12. 1, BA. 4 and BA. 5

Q Wang, Y Guo, S Iketani, MS Nair, Z Li, H Mohri… - Nature, 2022 - nature.com
… For antibody combinations previously authorized or approved for clinical use, all showed
a substantial loss of activity in vitro against BA.2.12.1 and BA.4/5. As for a mAb directed to the …