[HTML][HTML] SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape

TN Starr, N Czudnochowski, Z Liu, F Zatta, YJ Park… - Nature, 2021 - nature.com
… and potency across a panel of SARS-CoV-2 antibodies targeting the receptor-binding …
antibodies with exceptional sarbecovirus breadth and a corresponding resistance to SARS-CoV

Development of multi-specific humanized llama antibodies blocking SARS-CoV-2/ACE2 interaction with high affinity and avidity

J Dong, B Huang, Z Jia, B Wang… - Emerging Microbes & …, 2020 - Taylor & Francis
antibodies are promising agents against SARS-CoV-2. Here we describe using humanized
llama antibody VHHs against SARS-CoV-… polyclonal and monoclonal combination therapies. …

[HTML][HTML] Cross-reactive SARS-CoV-2 neutralizing antibodies from deep mining of early patient responses

G Bullen, JD Galson, G Hall, P Villar, L Moreels… - Frontiers in …, 2021 - frontiersin.org
… The majority of these neutralizing antibodies have been … of anti-SARS-CoV-2 antibodies
from the antibody repertoires of … Effect of the antibodies combinations was evaluated in the …

[HTML][HTML] Broadly neutralizing antibodies to SARS-CoV-2 and other human coronaviruses

Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
antibodies that target four key regions within the SARS-CoV-2 spike … against infection by
SARS-CoV-2 and other SARS-like … , and these antibodies could be used in combination with the …

[HTML][HTML] Influence of treatment with neutralizing monoclonal antibodies on the SARS-CoV-2 nasopharyngeal load and quasispecies

C Vellas, A Del Bello, A Debard, Z Steinmeyer… - Clinical Microbiology …, 2022 - Elsevier
… The NP SARS-CoV-2 viral load of mAb-treated patients decreased from 8.2 log 10 copies/…
Two patients harboured SARS-CoV-2 variants with a Q493R spike mutation 7 days after …

Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization

Z Liu, LA VanBlargan, LM Bloyet, PW Rothlauf… - BioRxiv, 2020 - biorxiv.org
antibody combinations could be isolated, we undertook a third selection campaign using a
combination … We were unable to isolate mutants resistant to the two antibodies when added …

[PDF][PDF] Enhancement versus neutralization by SARS-CoV-2 antibodies from a convalescent donor associates with distinct epitopes on the RBD

Y Zhou, Z Liu, S Li, W Xu, Q Zhang, IT Silva, C Li, Y Wu… - Cell Reports, 2021 - cell.com
Antibodies with the same combination of IGH and IGL variable gene sequences and closely
related CDR3s were grouped together and represented as a slice. In total, 25 slices were …

[HTML][HTML] Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization

D Planas, D Veyer, A Baidaliuk, I Staropoli… - Nature, 2021 - nature.com
… We studied the cross-reactivity of monoclonal antibodies to pre-existing SARS-CoV-2
strains, sera from convalescent individuals six or twelve months after the onset of COVID-19 …

[HTML][HTML] Antibodies and vaccines target RBD of SARS-CoV-2

L Min, Q Sun - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
antibodies that target the RBD of SARS-CoV-2 is essential in the design of the SARS-CoV-2 …
Recently, some studies showed that the combination of two antibodies, LY-CoV555 and LY-…

Antibody responses to SARS-CoV-2 in COVID-19 patients: the perspective application of serological tests in clinical practice

Q Long, H Deng, J Chen, J Hu, B Liu, P Liao, Y Lin… - MedRxiv, 2020 - medrxiv.org
… the feature of acute antibody response to SARS-CoV-2. A cohort of 52 COVID-19
suspects and 64 close contacts were enrolled to evaluate the potentiality of the antibody test. …