… These RBD antibodies ameliorate SARS-CoV-2 infection in mice … antibodyrecognition and neutralization highlights both potent single antibodies and stereotypic classes of antibodies …
… in antibody therapeutics and vaccines that induce antibodies to severe acute respiratory … coronavirus 2 (SARS-CoV-2). Many potently neutralizing anti-SARS-CoV-2 antibodies target the …
… to understand the molecular basis for immune recognition of SARS-CoV-2 spike (S) … for SARS-CoV-2 neutralization, we determined the structures of two human monoclonal antibodies …
Y Chen, X Zhao, H Zhou, H Zhu, S Jiang… - Nature Reviews …, 2023 - nature.com
… Moreover, S309 can broadly neutralize sarbecoviruses, including all currently identified SARS-CoV-2 VOC, as the epitope sequences recognized by S309 are highly conserved among …
D Li, GD Sempowski, KO Saunders… - Annual review of …, 2022 - annualreviews.org
… vary according to recognition epitopes. Several potent … that have antibody-escape mutations and the potential for antibody-… representative SARS-CoV-2 neutralizing antibodies that have …
… Fabs, revealing recognition of both S1 A and RBD epitopes on SARS-CoV-2 … SARS-CoV-2 spike mutations. Overall, our studies structurally define a recurrent anti-SARS-CoV-2 antibody …
… First, neutralizing monoclonal antibodies that target the SARS-CoV-2 RBM can prevent the virus from binding to ACE2, and are therefore promising antiviral drugs. Our structure has laid …
… infection of authentic SARS-CoV-2 and recombinant VSV/SARS-CoV-2 viruses. We … SARS-CoV-2 S neutralization escape variants. Mechanistic studies showed that these antibodies …
… ” antibodies revealed an NTD epitope that is recurrently mutated among emerging SARS-CoV-2 … and other non-RBD plasma antibodies are prevalent and have implications for SARS-…