Cytokine storm induced by SARS-CoV-2

P Song, W Li, J Xie, Y Hou, C You - Clinica chimica acta, 2020 - Elsevier
… suppress cytokine storm is essential … SARS-CoV-2 and the mechanisms by which cytokine
storm is induced by the virus will be introduced in detail, including the ways in which cytokines

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… the cytokine storm induced by COVID-19. In addition, we suggest that the identification and
treatment of the cytokine storm … innate responses to SARS-CoV-2 may cause cytokine storms. …

SARS-CoV-2 causes a different cytokine response compared to other cytokine storm-causing respiratory viruses in severely ill patients

M Olbei, I Hautefort, D Modos, A Treveil… - Frontiers in …, 2021 - frontiersin.org
cytokine responses caused by these viruses. Our curation indicates that the cytokine response
induced by SARS-CoV-2 … , as SARS-CoV-2 does not always induce specific cytokines like …

The role of IL-6 and other mediators in the cytokine storm associated with SARS-CoV-2 infection

A Copaescu, O Smibert, A Gibson, EJ Phillips… - Journal of Allergy and …, 2020 - Elsevier
… with severe acute respiratory syndrome coronavirus 2, leading to clinical … to as cytokine
storm in its severest form has been marked by elevation of IL-6, IL-10, TNF-α, and other cytokines

Role of toll‐like receptors in modulation of cytokine storm signaling in SARSCoV‐2‐induced COVID‐19

M Manik, RK Singh - Journal of medical virology, 2022 - Wiley Online Library
… The level of IL-6 is found to be significantly elevated in the serum of SARS-COV-2 patients
during cytokine storms. IL-6 inactivates cell-mediated antiviral response by inhibiting the …

SARS-CoV-2: a storm is raging

SF Pedersen, YC Ho - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
cytokines are likely produced by highly inflammatory macrophages that have been implicated
in cytokine storm … This study demonstrates that cytokine storm is associated with COVID-19 …

Cytokine storm induced by SARS-CoV-2 infection: The spectrum of its neurological manifestations

P Thepmankorn, J Bach, A Lasfar, X Zhao, S Souayah… - Cytokine, 2021 - Elsevier
coronavirus 2 (SARS-CoV-2), can trigger a hyperinflammatory state characterized by
elevated cytokine levels known as hypercytokinemia or cytokine storm, … routes of SARS-CoV-2 …

Cytokine storm and leukocyte changes in mild versus severe SARS-CoV-2 infection: Review of 3939 COVID-19 patients in China and emerging pathogenesis and …

J Wang, M Jiang, X Chen… - Journal of Leucocyte …, 2020 - academic.oup.com
… In examining leukocyte and cytokinecytokine responses lead to disease and/or organ
damage. By better understanding the mechanisms that drive the intensity of a cytokine storm, we …

Cytokine storm syndrome in SARS-CoV-2 infections: a functional role of mast cells

B Hafezi, L Chan, JP Knapp, N Karimi, K Alizadeh… - Cells, 2021 - mdpi.com
… Here, we summarize the pharmacologic therapies that have the potential to suppress
SARS-CoV-2-induced cytokine storms (Table 1). The medications that target the performance of …

[PDF][PDF] ORF8 contributes to cytokine storm during SARS-CoV-2 infection by activating IL-17 pathway

X Lin, B Fu, S Yin, Z Li, H Liu, H Zhang, N Xing, Y Wang… - Iscience, 2021 - cell.com
… that SARS-CoV-2 coding protein open reading frame 8 (ORF8) acted as a contributing factor
to cytokine storm … the pathogenesis of cytokine storm caused by SARS-CoV-2 and provide a …