Sensing of SARS-CoV-2 by pDCs and their subsequent production of IFN-I contribute to macrophage-induced cytokine storm during COVID-19

P Laurent, C Yang, AF Rendeiro… - Science …, 2022 - science.org
… pDCs are at the eye of the storm In severe COVID-19, macrophages induce cytokine storms,
… not directly infected by SARS-CoV-2, so how this cytokine storm is induced remains unclear. …

Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population

A Ciabattini, P Garagnani, F Santoro… - Seminars in …, 2020 - Springer
… risk of COVID-19-related “cytokine storm syndrome” with an overlap between the … of
SARS-CoV-2 infection. The complex and still unclear immunopathological mechanisms of SARS-CoV

[HTML][HTML] A network-based analysis reveals the mechanism underlying vitamin D in suppressing cytokine storm and virus in SARS-CoV-2 infection

F Ahmed - Frontiers in immunology, 2020 - frontiersin.org
… of pro-inflammatory cytokines through … cytokine storm in SARS-CoV-2 infection. The proposed
underlying mechanism of Vitamin D could be promising in suppressing the cytokine storm

Cytokine storm syndrome in coronavirus disease 2019: A narrative review

YM Gao, G Xu, B Wang, BC Liu - Journal of internal medicine, 2021 - Wiley Online Library
… some differences from the cytokine storms in other clinical settings… pathogenesis of cytokine
storm induced by SARS-CoV-2. … an important role in cytokine storm induced by SARS-CoV-2. …

Role of SARS-CoV-2-induced cytokine storm in multi-organ failure: Molecular pathways and potential therapeutic options

Y Nazerian, M Ghasemi, Y Yassaghi, A Nazerian… - International …, 2022 - Elsevier
… Furthermore, cytokine storm can cause post-COVID-19 … in COVID-19-related cytokine
storm and its association with multi-… targets to control cytokine storm wishing to answer unmet …

Effectiveness of corticoid pulses in patients with cytokine storm syndrome induced by SARS-CoV-2 infection

JLC Rubio, JDL Del Castillo… - … Clínica (English Edition), 2020 - Elsevier
SARS-CoV-2 disease (COVID-19).1, 2 The basis of its treatment is essentially tocilizumab,
an anti-IL-6 … other diseases in which there is a cytokine storm similar to the one that occurs in …

SARS-CoV-2 mediated lung inflammatory responses in host: targeting the cytokine storm for therapeutic interventions

P Asrani, MI Hassan - Molecular and Cellular Biochemistry, 2021 - Springer
cytokine storm formation and immune responses in COVID-19 infected host. Binding of
SARS-CoV… production of pro-inflammatory cytokines, cytokine storm, and immune responses in …

CD147 antibody specifically and effectively inhibits infection and cytokine storm of SARS-CoV-2 and its variants delta, alpha, beta, and gamma

J Geng, L Chen, Y Yuan, K Wang, Y Wang… - Signal transduction and …, 2021 - nature.com
… -related cytokine storm is induced by a “spike protein-CD147-CyPA signaling axis”: Infection
of SARS-CoV-… Consequently, the MAPK pathway regulated the expression of cytokines and …

[PDF][PDF] Mast cells activated by SARS-CoV-2 release histamine which increases IL-1 levels causing cytokine storm and inflammatory reaction in COVID-19

P Conti, A Caraffa, G Tetè, CE Gallenga… - J Biol Regul Homeost …, 2020 - researchgate.net
… -2 release histamine which increases IL-1 levels involved in cytokine storm and, … by
SARS-CoV-2 are involved in viral inflammation, contributing to the formation of the cytokine storm by …

Immune response to SARSCoV‐2 and mechanisms of immunopathological changes in COVID‐19

AK Azkur, M Akdis, D Azkur, M Sokolowska… - Allergy, 2020 - Wiley Online Library
… clinical conditions such as cytokine storm, acute respiratory … tissue damage, a cytokine
storm leading to acute respiratory … , a cytokine storm starts with extensive activation of cytokine-…