Structural insights into SARS-CoV-2 proteins

R Arya, S Kumari, B Pandey, H Mistry, SC Bihani… - Journal of molecular …, 2021 - Elsevier
… these structures to atomic details provided important insights … of these structures are also
useful as a target for the structure-… the available structural information on SARS-CoV-2 proteins. …

SARSCoV‐2, the pandemic coronavirus: Molecular and structural insights

SB Kadam, GS Sukhramani, P Bishnoi… - Journal of basic …, 2021 - Wiley Online Library
… the molecular aspects of SARS-CoV-2 including secondary structures in the genome and …
spread of the SARS-CoV-2. The mutations and the haplotypes reported in the SARS-CoV-2 …

Evolutionary and structural insights about potential SARS-CoV-2 evasion of nirmatrelvir

KS Yang, SZ Leeuwon, S Xu… - Journal of medicinal …, 2022 - ACS Publications
The US FDA approval of PAXLOVID, a combination therapy of nirmatrelvir and ritonavir has
significantly boosted our morale in fighting the COVID-19 pandemic. Nirmatrelvir is an …

Structural insight into the role of novel SARS-CoV-2 E protein: A potential target for vaccine development and other therapeutic strategies

M Sarkar, S Saha - PloS one, 2020 - journals.plos.org
… Thus, this study gives a structural insight into the putative mechanism of action of the
novel SARS-CoV-2 E protein as a conformation-dependent ion channel conducting H + ions. …

[HTML][HTML] Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach

AAT Naqvi, K Fatima, T Mohammad, U Fatima… - … et Biophysica Acta (BBA …, 2020 - Elsevier
… Further, this analysis provides a brief insight into the non-structural proteome as well …
SARS-CoV-2 polyprotein that may be useful to understand the structural basis of infection, structure-…

Structural insight reveals SARS-CoV-2 ORF7a as an immunomodulating factor for human CD14+ monocytes

Z Zhou, C Huang, Z Zhou, Z Huang, L Su, S Kang… - IScience, 2021 - cell.com
… of SARS-CoV-2 ORF7a and SARS-CoV ORF7a to human CD14 + monocytes, we solved the
structure of SARS-CoV-2 … Briefly, residues 14–96 of the SARS-CoV-2 ORF7a protein were …

[HTML][HTML] Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia

D Asarnow, B Wang, WH Lee, Y Hu, CW Huang… - Cell, 2021 - cell.com
… as severe acute respiratory syndrome coronavirus (SARS-CoV) and severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) is binding … Structural insights into coronavirus entry. …

Structural insights into coronavirus entry

MA Tortorici, D Veesler - Advances in virus research, 2019 - Elsevier
… The severe acute respiratory syndrome coronavirus (SARS-CoV) … The Middle-East respiratory
syndrome coronavirus (MERS-CoV) … SARS-CoV and MERS-CoV are zoonotic viruses that …

[HTML][HTML] Structural insights into the mechanism of RNA recognition by the N-terminal RNA-binding domain of the SARS-CoV-2 nucleocapsid phosphoprotein

A Khan, MT Khan, S Saleem, M Junaid, A Ali… - … and structural …, 2020 - Elsevier
… submitted the solution NMR structure of the SARs-CoV-2 nucleocapsid phosphoprotein (PDB
ID: 6YI3) was extracted from Protein Data Bank [20]. The structure was subjected to …

The SARS-CoV-2 spike glycoprotein as a drug and vaccine target: structural insights into its complexes with ACE2 and antibodies

AC Papageorgiou, I Mohsin - Cells, 2020 - mdpi.com
… of SARS-CoV-2 and its interactions with ACE2 and antibodies. Structural information of
SARS-CoV… key input for the development of therapies and vaccines against the new coronavirus. …