… of the different cytokines involved. We also discuss the induction, function, … signaling, and
existing and potential interventions for targeting these cytokines or related signal pathways. We …

… Cytokine storm syndrome (CSS) has … these cytokine-mediated inflammatory PCD pathways
as ‘PANoptosis’, a PCD activated by pathogens, such as influenza A virus (IAV), by cytokines, …

… immune responses of pathogenic Th1 cells and intermediate CD14 + CD16 + monocytes
are mediated by membrane-bound immune receptors and downstream signaling pathways. …

… The binding of TLRs occurs with the virus and may lead to the activation of NF-κB and
MAPK signaling pathways to facilitate viral clearance and produce antiviral responses. To …

… cytokine storm is induced by the virus will be introduced in detail, including the ways in which
cytokines … NF-κB transcriptional signaling pathway and the binding site of the nuclear factor …

… The IL-6 ‘classical’ pathway involves the IL-6 receptor (IL-6 R) which binds directly to gp130.
The ‘trans’ signaling pathway uses soluble sIL-6 receptors to aid gp130 binding and signal …

… The final activation sequence involves the NF-κB cross-talk with numerous cytokine and
TLR-mediated cell signalling pathways that depend upon the binding of TNFα and IL-1 to TLR4. …

… and there are two types of signaling pathways (classical and trans signaling pathway) have
… the classical pathway, IL-6 bind to its receptor ie mIL-6R (membrane bound receptor for IL-6) …

… (10) use the transcriptome dataset approach to discover that SARS-CoV-2 can activate
apoptosis and P53 signaling pathway (one of the pathways responsible for the survival of the cell…

… ACE2 and AT1R leading to the cytokine storm progression. b) Produced IFNs-I bind to the
related receptors and launching their signaling pathways results in the nuclear translocation of …