Weathering the cytokine storm in COVID-19: therapeutic implications

G Iannaccone, R Scacciavillani, MG Del Buono… - Cardiorenal …, 2020 - karger.com
cytokine release in response to viral infection, a condition known as cytokine release
syndrome (CRS) or cytokine storm… timed anti-inflammatory therapeutic strategies could improve …

The cytokine storm and COVID‐19

B Hu, S Huang, L Yin - Journal of medical virology, 2021 - Wiley Online Library
… However, a meta-analysis of clinical trials indicated no clinical benefits of HCQ treatment
in … Early control of the cytokine storm through therapies, such as immunomodulators and …

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
… of therapeutic plasma exchange (TPE) to treat cytokine stormcytokines from the blood
and can improve cytokine storm 7 . … have demonstrated the clinical benefits of TPE in severe …

Cytokine storm in COVID-19: the current evidence and treatment strategies

Y Tang, J Liu, D Zhang, Z Xu, J Ji, C Wen - Frontiers in immunology, 2020 - frontiersin.org
… T-cell therapy could help to distinguish CRS from a cytokine storm (2)… laboratory criteria to
identify the cytokine storm. In this review… corticosteroids might have some benefit for critically ill …

Pathogenesis and treatment of cytokine storm induced by infectious diseases

XD Tang, TT Ji, JR Dong, H Feng, FQ Chen… - International journal of …, 2021 - mdpi.com
… underlying cytokine storm induction … cytokine storms are described from both host and
pathogen perspectives. In summary, current studies indicate that cytokine storm-targeted therapies

The signal pathways and treatment of cytokine storm in COVID-19

L Yang, X Xie, Z Tu, J Fu, D Xu, Y Zhou - … and targeted therapy, 2021 - nature.com
… Reports of hemophagocytosis and clinical benefits from cytokine-targeted therapies in
severe COVID-19 patients further confirmed the existence and pathogenesis of COVID-CS. …

Constitutive inflammatory cytokine storm: a major threat to human health

KK Gupta, MA Khan, SK Singh - Journal of Interferon & Cytokine …, 2020 - liebertpub.com
therapies and monoclonal antibodies cause cytokine release syndrome. Efforts are being
carried out to maximize the chance for therapeutic benefit from … of sustained cytokine release. …

Cytokine storm in COVID-19: immunopathogenesis and therapy

C Zanza, T Romenskaya, AC Manetti, F Franceschi… - Medicina, 2022 - mdpi.com
cytokine storm is a hyperinflammatory state secondary to the excessive production of cytokines
… The term cytokine storm was first used in 1993 to describe the graft-versus-host disease …

Review on therapeutic targets for COVID-19: insights from cytokine storm

ML de Mélo Silva Júnior, LMA de Souza… - Postgraduate …, 2021 - academic.oup.com
… (cytokine storm) and tissue damage. Some drugs have been studied as therapeutic targets
(block to viral entry or to cytokine storm) … A study with control group showed no benefit from …

Cytokine storm and probable role of immunoregulatory drugs in COVID-19: a comprehensive review

A Sadeghzadeh-Bazargan, E Behrangi… - Iranian Journal of …, 2020 - iranjd.ir
… of the inflammatory response and cytokine storm in increased … It is important to select
patients who may benefit from these … along with suggested antiviral therapies can be effective in …