Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions

Y Jamilloux, T Henry, A Belot, S Viel, M Fauter… - Autoimmunity …, 2020 - Elsevier
… Next, reviewing current evidence drawn from clinical trials, … not discuss antiviral strategies
used to treat COVID-19, nor will … have paralleled the COVID-19 cytokine storm to either primary …

Anticoagulant treatment in COVID-19: a narrative review

V Carfora, G Spiniello, R Ricciolino, M Di Mauro… - Journal of thrombosis …, 2021 - Springer
… endothelial dysfunction, cytokine storm and complement … therapy of COVID 19-related
thrombosis disease, focusing on the available evidence on the possible treatment strategies

Cytokine storm and COVID-19: a chronicle of pro-inflammatory cytokines

A Fara, Z Mitrev, RA Rosalia, BM Assas - Open biology, 2020 - royalsocietypublishing.org
… Notably, evidence for IL-6 production enhancement in SARS-… to new possible strategies for
therapeutic interventions [65]. … 2020 Acute kidney injury in COVID-19: emerging evidence of …

Dexamethasone to combat cytokine storm in COVID-19: Clinical trials and preliminary evidence

K Sharun, R Tiwari, J Dhama… - International Journal of …, 2020 - journals.lww.com
present our analysis of the current evidence and preliminary findings regarding the use of
dexamethasone to combat the SARS-CoV-2-induced cytokine storm… Another strategy to reduce …

COVID-19 cytokine storm: The anger of inflammation

M Mahmudpour, J Roozbeh, M Keshavarz, S Farrokhi… - Cytokine, 2020 - Elsevier
therapeutic strategies to confront the cytokine storm in order to prevent and treat COVID-19
In a recent study, the first clinical evidence has shown that ACE inhibitors or ARB therapy in …

… cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to counter cytokine storm

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
… The use of corticosteroids may be an efficient strategy to treat acute COVID-19 patients,
particularly those who require mechanical ventilators [104,131,136]. Interferons form an …

[HTML][HTML] A research update: significance of cytokine storm and diaphragm in COVID-19

A Mittal, A Dua, S Gupta, E Injeti - Current Research in Pharmacology and …, 2021 - Elsevier
… In their review of current evidence and treatment strategies for COVID-19, Tang et al.,
summarizes other studies that indicate poor prognosis in patients with higher levels of these …

[HTML][HTML] Potential of natural astaxanthin in alleviating the risk of cytokine storm in COVID-19

J Talukdar, B Bhadra, T Dattaroy, V Nagle… - Biomedicine & …, 2020 - Elsevier
… the management of cytokine storm (CS) in COVID-19. Here, we provide an overview of the
available evidence on … have been repurposed as a therapeutic strategy to alleviate the risk of …

Weathering the COVID-19 storm: Lessons from hematologic cytokine syndromes

JT England, A Abdulla, CM Biggs, AYY Lee, KA Hay… - Blood Reviews, 2021 - Elsevier
… We review the evidence for cytokine blockade and … in COVID-CSS and inform strategies for
therapeutic intervention. In this … in other cytokine storm disorders including IL-2R, IL-6, IL-10, …

[HTML][HTML] Are mesenchymal stem cells able to manage cytokine storm in COVID-19 patients? A review of recent studies

NK Farkhad, H Reihani, AA Moghadam… - … Therapy, 2021 - Elsevier
… much evidence from the cytokine profile of Covid-19 patients, indicating that cytokine storm
is … strategies to improve critically Covid-19 patients with severe lung involvement is to prevent …