… To define the top DEG, we selected genes with an FDR < … We have shown earlier that IL27
displays antiviral properties … antiviral state in MDMs and reduce CHIKV replication in vitro. …

… -induced DNA leakage, as described for RNA viruses before [… Virus was produced by in
vitro-transcription of and … of its genome, selecting specifically full genomic RNA to be packaged …

… C virus (HCV) is a positive-sense single-stranded RNA virus … as a robust and widely used
in vitro infection model for HCV. … III IFN family comprises IFN-λ1, IFN-λ2 IFN-λ3 and IFN-λ4. …

… We showed that IFN-λ1 expression correlated with NS5B … Similar to host RNAs, genomes
of many RNA virus families are … In this work, we aimed to simulate a persistent infection in vitro …

… ileum epithelium) as an in vitro model to investigate the potential … Therefore, nsp1 was
selected for further investigation. To … As the largest known RNA viruses, CoVs including SARS-…

… IFN-β or IFN-λ1 decreases the strength of the antiviral activity of … in the treatment of infections
by RNA viruses in both rodents and … The potent in vitro anti-RSV activity of MEDS433 and its …

… for detecting the viral RNA from RNA viruses in the cytosol, … The human IFN-λ family, IFN-λ1,
IFN-λ2 and IFN-λ3 all exhibit … ) and ISGs production in vitro. The most common form of IFN-…

… In vitro studies revealed that IFNλs could induce apoptosis in … Notably, a phase 3 clinical
trial using pegylated IFN-λ1 … RNA viruses that replicate in the cytoplasm produce webs of …

… by suppressing viral spread in the early stages of infection … Source 15S was selected
because of higher flow rates and … 3c shows all steps of target protein purification. The presence …

… established GBM cell lines in vitro by the same virus dose (Fig. … T cells were isolated by
negative selection and adoptively … potential of MDA5 signaling/RNA virus replication in the TME …