… As a major peptide hormone and growth factor, glucagon-like peptide 1 (GLP-1) regulates
several physiological processes in the body and brain. GLP-1 is produced in enteroendocrine …

… are likely to develop a more chronic course, emerging evidence including our own studies
suggest that IR and related inflammatory pathways lead to impairments in blood-brain barrier (…

… of astrogliosis, maintenance of blood–brain barrier integrity, the … central finding of the
present study that the highly selective GLP-1R antagonist Ex9 blocks the neuroprotective effect …

… proteins by crossing the blood-brain barrier. The purpose of … (in astrocytes and blood-brain
barrier endothelial cells) and … many brain regions throughout the central nervous system, …

… These include breakdown of the blood-brain barrier (BBB), 3 changes to blood flow, 4 … is
believed to be one of the main crucial precursor events that underlies neuronal dysfunction 1 …

… blood brain barrier (BBB) and act on the central nervous system (CNS), associated with weight
reduction effect… Keywords: Glucagon-Like Peptide 1 (GLP-1), GLP-1 receptor agonist (GLP…

… was to determine if central glucagon action plays a physiologic … through activation of glucagon
and glucagon-like peptide-1 (… labeled somatostatin crossed the blood-brain barrier in vivo (…

… to the incretin hormone glucagon-like peptide-1. … The central nervous system contains
only small amounts of the peptide 7 and it is unclear whether it crosses the blood–brain barrier. …

… The main aim of the current study was to investigate the central and peripheral effects of
liraglutide in rats under normal physiological conditions and diabetic conditions. In addition, the …

… paid to the protective effect of GLP-1 and its analogues on the central nervous system. A …
nourish neurons by entering the blood-brain barrier. This effect is mainly mediated by activation …